Family history and perceived risk of diabetes, cardiovascular disease, cancer, and depression

Show simple item record

dc.contributor University of Helsinki, Department of Social Research (2010-2017) en
dc.contributor University of Helsinki, Department of Social Research (2010-2017) en
dc.contributor University of Helsinki, Department of Social Research (2010-2017) en
dc.contributor.author Vornanen, Marleena Emilia
dc.contributor.author Konttinen, Hanna Marja
dc.contributor.author Kääriäinen, Helena
dc.contributor.author Mannisto, Satu
dc.contributor.author Salomaa, Veikko
dc.contributor.author Perola, Markus
dc.contributor.author Haukkala, Ari Heikki
dc.date.accessioned 2018-02-21T08:14:06Z
dc.date.available 2018-02-21T08:14:06Z
dc.date.issued 2016
dc.identifier.citation Vornanen , M E , Konttinen , H M , Kääriäinen , H , Mannisto , S , Salomaa , V , Perola , M & Haukkala , A H 2016 , ' Family history and perceived risk of diabetes, cardiovascular disease, cancer, and depression ' , Preventive Medicine , vol. 90 , pp. 177-183 . https://doi.org/10.1016/j.ypmed.2016.06.027 en
dc.identifier.issn 0091-7435
dc.identifier.other PURE: 77200004
dc.identifier.other PURE UUID: f6dcd8eb-5534-43da-9a41-27f119f6501c
dc.identifier.other Scopus: 84978712471
dc.identifier.other WOS: 000388318000025
dc.identifier.other ORCID: /0000-0002-6001-4418/work/40902906
dc.identifier.other ORCID: /0000-0001-8567-1548/work/29916241
dc.identifier.uri http://hdl.handle.net/10138/232666
dc.description.abstract Background: Family history is a useful and inexpensive tool to assess risks of multifactorial diseases. Family history enables individualized disease prevention, but its effects on perceived risks of various diseases need to be understood in more detail. We examined how family history relates to perceived risk of diabetes mellitus, cardiovascular disease (CVD), cancer, and depression, and whether these associations are independent of or moderated by sociodemographic factors, health behavior/weight status (smoking, alcohol consumption, physical activity, BMI [kg/m²]), or depressive symptoms. Methods: Participants were Finnish 25−74-year-olds (N=6258) from a population-based FINRISK 2007 study. Perceived absolute lifetime risks (1–5) and first-degree family history of CVD, diabetes, cancer and depression, and health behaviors were self-reported. Weight and height were measured in a health examination. Results: Family history was most prevalent for cancer (36.7 %), least for depression (19.6 %). Perceived risk mean was highest for CVD (2.8), lowest for depression (2.0). Association between family history and perceived risk was strongest for diabetes (β=0.34, P<0.001), weakest for depression (β=0.19, P<0.001). Adjusting for sociodemographics, health behavior, and depressive symptoms did not change these associations. The association between family history and perceived risk tended to be stronger among younger than among older adults, but similar regardless of health behaviors or depressive symptoms. Discussion: Association between family history and perceived risk varies across diseases. People’s current understandings on heritability need to be acknowledged in risk communication practices. Future research should seek to identify effective strategies to combine familial and genetic risk communication in disease prevention. en
dc.format.extent 7
dc.language.iso eng
dc.relation.ispartof Preventive Medicine
dc.rights en
dc.subject 3142 Public health care science, environmental and occupational health en
dc.title Family history and perceived risk of diabetes, cardiovascular disease, cancer, and depression en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.1016/j.ypmed.2016.06.027
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/acceptedVersion
dc.contributor.pbl
dc.contributor.pbl
dc.contributor.pbl
dc.contributor.pbl

Files in this item

Total number of downloads: Loading...

Files Size Format View
unproofed_online_version.pdf 308.6Kb PDF View/Open

This item appears in the following Collection(s)

Show simple item record