Outcome after relapse of myelodysplastic syndrome and secondary acute myeloid leukemia following allogeneic stem cell transplantation : a retrospective registry analysis on 698 patients by the Chronic Malignancies Working Party of the European Society of Blood and Marrow Transplantation

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Schmid , C , de Wreede , L C , van Biezen , A , Finke , J , Ehninger , G , Ganser , A , Volin , L , Niederwieser , D , Beelen , D , Alessandrino , P , Kanz , L , Schleuning , M , Passweg , J , Veelken , H , Maertens , J , Cornelissen , J J , Blaise , D , Gramatzki , M , Milpied , N , Yakoub-Agha , I , Mufti , G , Rovira , M , Arnold , R , de Witte , T , Robin , M & Kroeger , N 2018 , ' Outcome after relapse of myelodysplastic syndrome and secondary acute myeloid leukemia following allogeneic stem cell transplantation : a retrospective registry analysis on 698 patients by the Chronic Malignancies Working Party of the European Society of Blood and Marrow Transplantation ' , Haematologica , vol. 103 , no. 2 , pp. 237-245 . https://doi.org/10.3324/haematol.2017.168716

Title: Outcome after relapse of myelodysplastic syndrome and secondary acute myeloid leukemia following allogeneic stem cell transplantation : a retrospective registry analysis on 698 patients by the Chronic Malignancies Working Party of the European Society of Blood and Marrow Transplantation
Author: Schmid, Christoph; de Wreede, Liesbeth C.; van Biezen, Anja; Finke, Juergen; Ehninger, Gerhard; Ganser, Arnold; Volin, Liisa; Niederwieser, Dietger; Beelen, Dietrich; Alessandrino, Paolo; Kanz, Lothar; Schleuning, Michael; Passweg, Jakob; Veelken, Hendrik; Maertens, Johan; Cornelissen, Jan J.; Blaise, Didier; Gramatzki, Martin; Milpied, Noel; Yakoub-Agha, Ibrahim; Mufti, Ghulam; Rovira, Montserrat; Arnold, Renate; de Witte, Theo; Robin, Marie; Kroeger, Nikolaus
Contributor organization: Clinicum
Hematologian yksikkö
Department of Oncology
HUS Comprehensive Cancer Center
Date: 2018-02
Language: eng
Number of pages: 9
Belongs to series: Haematologica
ISSN: 0390-6078
DOI: https://doi.org/10.3324/haematol.2017.168716
URI: http://hdl.handle.net/10138/233483
Abstract: No standard exists for the treatment of myelodysplastic syndrome relapsing after allogeneic stem cell transplantation. We performed a retrospective registry analysis of outcomes and risk factors in 698 patients, treated with different strategies. The median overall survival from relapse was 4.7 months (95% confidence interval: 4.1-5.3) and the 2-year survival rate was 17.7% (95% confidence interval: 14.8-21.2%). Shorter remission after transplantation (P
Subject: DONOR LYMPHOCYTE INFUSIONS
LOW-DOSE AZACITIDINE
REGULATORY T-CELLS
HEMATOLOGICAL MALIGNANCIES
SALVAGE THERAPY
RISK-FACTORS
AML
ADULTS
EBMT
CHEMOTHERAPY
3122 Cancers
Peer reviewed: Yes
Rights: cc_by_nc
Usage restriction: openAccess
Self-archived version: publishedVersion


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