Outcome after relapse of myelodysplastic syndrome and secondary acute myeloid leukemia following allogeneic stem cell transplantation : a retrospective registry analysis on 698 patients by the Chronic Malignancies Working Party of the European Society of Blood and Marrow Transplantation
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Schmid , C , de Wreede , L C , van Biezen , A , Finke , J , Ehninger , G , Ganser , A , Volin , L , Niederwieser , D , Beelen , D , Alessandrino , P , Kanz , L , Schleuning , M , Passweg , J , Veelken , H , Maertens , J , Cornelissen , J J , Blaise , D , Gramatzki , M , Milpied , N , Yakoub-Agha , I , Mufti , G , Rovira , M , Arnold , R , de Witte , T , Robin , M & Kroeger , N 2018 , ' Outcome after relapse of myelodysplastic syndrome and secondary acute myeloid leukemia following allogeneic stem cell transplantation : a retrospective registry analysis on 698 patients by the Chronic Malignancies Working Party of the European Society of Blood and Marrow Transplantation ' , Haematologica , vol. 103 , no. 2 , pp. 237-245 . https://doi.org/10.3324/haematol.2017.168716
| Title: | Outcome after relapse of myelodysplastic syndrome and secondary acute myeloid leukemia following allogeneic stem cell transplantation : a retrospective registry analysis on 698 patients by the Chronic Malignancies Working Party of the European Society of Blood and Marrow Transplantation |
| Author: | Schmid, Christoph; de Wreede, Liesbeth C.; van Biezen, Anja; Finke, Juergen; Ehninger, Gerhard; Ganser, Arnold; Volin, Liisa; Niederwieser, Dietger; Beelen, Dietrich; Alessandrino, Paolo; Kanz, Lothar; Schleuning, Michael; Passweg, Jakob; Veelken, Hendrik; Maertens, Johan; Cornelissen, Jan J.; Blaise, Didier; Gramatzki, Martin; Milpied, Noel; Yakoub-Agha, Ibrahim; Mufti, Ghulam; Rovira, Montserrat; Arnold, Renate; de Witte, Theo; Robin, Marie; Kroeger, Nikolaus |
| Contributor organization: | Clinicum Hematologian yksikkö Department of Oncology HUS Comprehensive Cancer Center |
| Date: | 2018-02 |
| Language: | eng |
| Number of pages: | 9 |
| Belongs to series: | Haematologica |
| ISSN: | 0390-6078 |
| DOI: | https://doi.org/10.3324/haematol.2017.168716 |
| URI: | http://hdl.handle.net/10138/233483 |
| Abstract: | No standard exists for the treatment of myelodysplastic syndrome relapsing after allogeneic stem cell transplantation. We performed a retrospective registry analysis of outcomes and risk factors in 698 patients, treated with different strategies. The median overall survival from relapse was 4.7 months (95% confidence interval: 4.1-5.3) and the 2-year survival rate was 17.7% (95% confidence interval: 14.8-21.2%). Shorter remission after transplantation (P |
| Subject: |
DONOR LYMPHOCYTE INFUSIONS
LOW-DOSE AZACITIDINE REGULATORY T-CELLS HEMATOLOGICAL MALIGNANCIES SALVAGE THERAPY RISK-FACTORS AML ADULTS EBMT CHEMOTHERAPY 3122 Cancers |
| Peer reviewed: | Yes |
| Rights: | cc_by_nc |
| Usage restriction: | openAccess |
| Self-archived version: | publishedVersion |
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