Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)

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Strandberg , T , Levalahti , E , Ngandu , T , Solomon , A , Kivipelto , M , Lehtisalo , J , Laatikainen , T , Soininen , H , Antikainen , R , Jula , A , Tuomilehto , J , Peltonen , M , Lindstrom , J , Rauramaa , R , Pajala , S , Hanninen , T , Solomon , A , Paajanen , T , Mangialasche , F & FINGER Study Grp 2017 , ' Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER) ' , European Geriatric Medicine , vol. 8 , no. 2 , pp. 164-167 .

Title: Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)
Author: Strandberg, T.; Levalahti, E.; Ngandu, T.; Solomon, A.; Kivipelto, M.; Lehtisalo, J.; Laatikainen, T.; Soininen, H.; Antikainen, R.; Jula, A.; Tuomilehto, J.; Peltonen, M.; Lindstrom, J.; Rauramaa, R.; Pajala, S.; Hanninen, T.; Solomon, A.; Paajanen, T.; Mangialasche, F.; FINGER Study Grp
Contributor organization: Clinicum
Department of Medicine
Timo Strandberg / Principal Investigator
Geriatrian yksikkö
HUS Internal Medicine and Rehabilitation
Date: 2017-04
Language: eng
Number of pages: 4
Belongs to series: European Geriatric Medicine
ISSN: 1878-7649
Abstract: Introduction: The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) successfully demonstrated that multidomain lifestyle intervention can improve or maintain cognitive functioning in at-risk individuals. Health-related quality of life (HRQoL) was a secondary endpoint. Methods: The intervention (n = 631) aimed at healthy diet, increased physical activity, cognitive training, and vascular risk management. The control group (n = 629) was given general health advice. HRQoL was assessed at baseline, 12, and 24 months using validated RAND-36 (SF-36) instrument with 8 scales. Results: During the 2-year intervention period, mean scores in all scales decreased in the control group, but increased in the intervention group for vitality (12 months), social function (12 months), and especially general health at both 12 and 24 months. There was a statistically significant beneficial effect of intervention on the change in general health and physical function at 12 and 24 months. Conclusion: Multidomain lifestyle intervention improved also important dimensions of HRQoL. (C) 2017 Elsevier Masson SAS and European Union Geriatric Medicine Society. All rights reserved.
Subject: Cognition
Health-related quality of life
3121 General medicine, internal medicine and other clinical medicine
Peer reviewed: Yes
Rights: unspecified
Usage restriction: openAccess
Self-archived version: publishedVersion

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