Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)

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Strandberg , T , Levalahti , E , Ngandu , T , Solomon , A , Kivipelto , M , Lehtisalo , J , Laatikainen , T , Soininen , H , Antikainen , R , Jula , A , Tuomilehto , J , Peltonen , M , Lindstrom , J , Rauramaa , R , Pajala , S , Hanninen , T , Solomon , A , Paajanen , T , Mangialasche , F & FINGER Study Grp 2017 , ' Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER) ' , European Geriatric Medicine , vol. 8 , no. 2 , pp. 164-167 . https://doi.org/10.1016/j.eurger.2016.12.005

Title: Health-related quality of life in a multidomain intervention trial to prevent cognitive decline (FINGER)
Author: Strandberg, T.; Levalahti, E.; Ngandu, T.; Solomon, A.; Kivipelto, M.; Lehtisalo, J.; Laatikainen, T.; Soininen, H.; Antikainen, R.; Jula, A.; Tuomilehto, J.; Peltonen, M.; Lindstrom, J.; Rauramaa, R.; Pajala, S.; Hanninen, T.; Solomon, A.; Paajanen, T.; Mangialasche, F.; FINGER Study Grp
Contributor: University of Helsinki, Clinicum
Date: 2017-04
Language: eng
Number of pages: 4
Belongs to series: European Geriatric Medicine
ISSN: 1878-7649
URI: http://hdl.handle.net/10138/235592
Abstract: Introduction: The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) successfully demonstrated that multidomain lifestyle intervention can improve or maintain cognitive functioning in at-risk individuals. Health-related quality of life (HRQoL) was a secondary endpoint. Methods: The intervention (n = 631) aimed at healthy diet, increased physical activity, cognitive training, and vascular risk management. The control group (n = 629) was given general health advice. HRQoL was assessed at baseline, 12, and 24 months using validated RAND-36 (SF-36) instrument with 8 scales. Results: During the 2-year intervention period, mean scores in all scales decreased in the control group, but increased in the intervention group for vitality (12 months), social function (12 months), and especially general health at both 12 and 24 months. There was a statistically significant beneficial effect of intervention on the change in general health and physical function at 12 and 24 months. Conclusion: Multidomain lifestyle intervention improved also important dimensions of HRQoL. (C) 2017 Elsevier Masson SAS and European Union Geriatric Medicine Society. All rights reserved.
Subject: Cognition
Prevention
Multidomain
Health-related quality of life
RAND-36
SF-36
SELF-RATED HEALTH
MORTALITY
MEN
EXERCISE
3121 General medicine, internal medicine and other clinical medicine
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