Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials

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Scala , G , Marwah , V , Kinaret , P , Sund , J , Fortino , V & Greco , D 2018 , ' Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials ' , Data in Brief , vol. 19 , pp. 1046-1057 . https://doi.org/10.1016/j.dib.2018.05.107

Title: Integration of genome-wide mRNA and miRNA expression, and DNA methylation data of three cell lines exposed to ten carbon nanomaterials
Author: Scala, Giovanni; Marwah, Veer; Kinaret, Pia; Sund, Jukka; Fortino, Vittorio; Greco, Dario
Contributor: University of Helsinki, University of Tampere
University of Helsinki, Institute of Biotechnology
University of Helsinki, University of Tampere
University of Helsinki, University of Tampere
University of Helsinki, Institute of Biotechnology
Date: 2018-08
Language: eng
Number of pages: 12
Belongs to series: Data in Brief
ISSN: 2352-3409
URI: http://hdl.handle.net/10138/236001
Abstract: We present data derived from an exposure experiment in which three cell-lines representative of cell types of the respiratory tissue (epithelial type-I A549, epithelial type-II BEAS-2B, and macrophage THP-1) have been exposed to ten different carbon-based nanomaterials for 48 h. In particular, we provide: genome-wide mRNA and miRNA expression, and DNA methylation; gene tables, containing information on the aberrations induced in these three genomic data layers at the gene level; mechanism of action (MOA) maps representing the comparative functional alteration induced in each cell line and each exposure. (C) 2018 Published by Elsevier Inc.
Subject: 1182 Biochemistry, cell and molecular biology
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