Manometric findings in relation to functional outcomes in different types of anorectal malformations

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dc.contributor.author Kyrklund, Kristiina
dc.contributor.author Pakarinen, Mikko P.
dc.contributor.author Rintala, Risto J.
dc.date.accessioned 2018-07-06T21:21:46Z
dc.date.available 2021-12-17T22:02:50Z
dc.date.issued 2017-04
dc.identifier.citation Kyrklund , K , Pakarinen , M P & Rintala , R J 2017 , ' Manometric findings in relation to functional outcomes in different types of anorectal malformations ' , Journal of Pediatric Surgery , vol. 52 , no. 4 , pp. 563-568 . https://doi.org/10.1016/j.jpedsurg.2016.08.025
dc.identifier.other PURE: 86548552
dc.identifier.other PURE UUID: db968014-f9b3-410c-bddf-42eced0449da
dc.identifier.other WOS: 000400423700011
dc.identifier.other Scopus: 84992709855
dc.identifier.uri http://hdl.handle.net/10138/236996
dc.description.abstract Aims: To compare anorectal manometry (AM) in patients with different types of anorectal malformations (ARMs) in relation to functional outcomes. Methods: A single-institution, cross-sectional study. After ethical approval, all patients >= 7 years old treated for anterior anus (AA), perineal fistula (PF), vestibular fistula (VF), or rectourethral fistula (RUF) from 1983 onwards were invited to answer the Rintala bowel function score (BFS) questionnaire and to attend anorectal manometry (AM). Patients with mild ARMs (AA females and PF males) had been treated with minimally invasive perineal procedures. Females with VF/PF and males with RUF had undergone internal-sphincter saving sagittal repairs. Results: 55 of 132 respondents (42%; median age 12 (7-29) years; 42% male) underwent AM. Patients with mild ARMs displayed good anorectal function after minimally invasive treatments. The median anal resting and squeeze pressures among patients with mild ARMs(60 cm H2O and 116 cm H2O respectively) were significantly higher than among patients with more severe ARMs (50 cm H2O, and 80 cm H2O respectively; p Conclusions: Our findings support the appropriateness of our minimally invasive approaches to the management of mild ARMs, and IAS-saving anatomical repairs for patients with more severe malformations. (C) 2017 Elsevier Inc. All rights reserved. en
dc.format.extent 6
dc.language.iso eng
dc.relation.ispartof Journal of Pediatric Surgery
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Anorectal malformations
dc.subject Anorectal manometry
dc.subject Fecal continence
dc.subject Bowel function
dc.subject Internal anal sphincter
dc.subject POSTERIOR SAGITTAL ANORECTOPLASTY
dc.subject TERM-FOLLOW-UP
dc.subject URINARY-TRACT SYMPTOMS
dc.subject BOWEL FUNCTION
dc.subject IMPERFORATE ANUS
dc.subject FECAL CONTINENCE
dc.subject VESTIBULAR FISTULA
dc.subject SPHINCTER FUNCTION
dc.subject CHILDREN
dc.subject CHILDHOOD
dc.subject 3123 Gynaecology and paediatrics
dc.subject 3126 Surgery, anesthesiology, intensive care, radiology
dc.title Manometric findings in relation to functional outcomes in different types of anorectal malformations en
dc.type Article
dc.contributor.organization Children's Hospital
dc.contributor.organization Clinicum
dc.contributor.organization University of Helsinki
dc.contributor.organization Lastenkirurgian yksikkö
dc.contributor.organization HUS Children and Adolescents
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.jpedsurg.2016.08.025
dc.relation.issn 0022-3468
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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