Association between adherence to dietary recommendations and high-sensitivity C-reactive protein level in type 1 diabetes

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Ahola , A J , Saraheimo , M , Freese , R , Forsblom , C , Mäkimattila , S , Groop , P-H & FinnDiane Study Grp 2017 , ' Association between adherence to dietary recommendations and high-sensitivity C-reactive protein level in type 1 diabetes ' , Diabetes Research and Clinical Practice , vol. 126 , pp. 122-128 . https://doi.org/10.1016/j.diabres.2017.02.012

Title: Association between adherence to dietary recommendations and high-sensitivity C-reactive protein level in type 1 diabetes
Author: Ahola, Aila J.; Saraheimo, Markku; Freese, Riitta; Forsblom, Carol; Mäkimattila, Sari; Groop, Per-Henrik; FinnDiane Study Grp
Contributor: University of Helsinki, Nefrologian yksikkö
University of Helsinki, Clinicum
University of Helsinki, Department of Food and Nutrition
University of Helsinki, Clinicum
University of Helsinki, Nefrologian yksikkö
University of Helsinki, Clinicum
Date: 2017-04
Language: eng
Number of pages: 7
Belongs to series: Diabetes Research and Clinical Practice
ISSN: 0168-8227
URI: http://hdl.handle.net/10138/237093
Abstract: Aims: Inflammation plays an important role in the pathogenesis of cardiovascular diseases. Diet, as a modifiable risk factor, may in turn impact systemic inflammation. We therefore assessed whether adherence to the dietary recommendations is associated with high-sensitivity C-reactive protein (hs-CRP) concentrations in type 1 diabetes. Methods: Cross-sectional data from 677 FinnDiane study participants (48% men, mean +/- standard deviation age 46 +/- 13 years) were included. Dietary intake was assessed with a self-administered questionnaire. A diet score, with higher values denoting better adherence to the recommendations, was calculated. Serum hs-CRP concentration was measured, and individuals with hs-CRP <1.0 mg/l, and hs-CRP > 3.0 but <10.0 mg/l were compared. Results: Men and women with high hs-CRP had higher BMI, waist circumference, and triglyceride concentration, but lower HDL-cholesterol concentration. Adjusted for BMI, mean diet score was higher in the low hs-CRP group, both in men (10.8 +/- 3.6 vs. 9.9 +/- 3.8, p = 0.023) and women (12.7 +/- 3.4 vs. 11.6 +/- 3.5, p = 0.021). After further adjustments with potential confounding factors, the difference remained significant only in men. Conclusions: A diet that more closely adheres to the dietary recommendations is associated with lower hs-CRP in men. A prudent diet may help reduce systemic inflammation in type 1 diabetes. (C) 2017 Elsevier B.V. All rights reserved.
Subject: Adherence to dietary
recommendations
hs-CRP
Low-grade inflammation
Type 1 diabetes
TIME PHYSICAL-ACTIVITY
SYSTEMIC INFLAMMATION
CARDIOVASCULAR RISK
ELDERLY POPULATION
OXIDATIVE STRESS
GLYCEMIC CONTROL
FIBER INTAKE
DISEASE
WOMEN
NEPHROPATHY
3121 Internal medicine
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