Association between adherence to dietary recommendations and high-sensitivity C-reactive protein level in type 1 diabetes

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Ahola , A J , Saraheimo , M , Freese , R , Forsblom , C , Mäkimattila , S , Groop , P-H & FinnDiane Study Grp 2017 , ' Association between adherence to dietary recommendations and high-sensitivity C-reactive protein level in type 1 diabetes ' , Diabetes Research and Clinical Practice , vol. 126 , pp. 122-128 . https://doi.org/10.1016/j.diabres.2017.02.012

Title: Association between adherence to dietary recommendations and high-sensitivity C-reactive protein level in type 1 diabetes
Author: Ahola, Aila J.; Saraheimo, Markku; Freese, Riitta; Forsblom, Carol; Mäkimattila, Sari; Groop, Per-Henrik; FinnDiane Study Grp
Contributor organization: Nefrologian yksikkö
Department of Medicine
Research Programs Unit
Diabetes and Obesity Research Program
Clinicum
Department of Food and Nutrition
Per Henrik Groop / Principal Investigator
Nutrition Science
HUS Abdominal Center
HUS Internal Medicine and Rehabilitation
Date: 2017-04
Language: eng
Number of pages: 7
Belongs to series: Diabetes Research and Clinical Practice
ISSN: 0168-8227
DOI: https://doi.org/10.1016/j.diabres.2017.02.012
URI: http://hdl.handle.net/10138/237093
Abstract: Aims: Inflammation plays an important role in the pathogenesis of cardiovascular diseases. Diet, as a modifiable risk factor, may in turn impact systemic inflammation. We therefore assessed whether adherence to the dietary recommendations is associated with high-sensitivity C-reactive protein (hs-CRP) concentrations in type 1 diabetes. Methods: Cross-sectional data from 677 FinnDiane study participants (48% men, mean +/- standard deviation age 46 +/- 13 years) were included. Dietary intake was assessed with a self-administered questionnaire. A diet score, with higher values denoting better adherence to the recommendations, was calculated. Serum hs-CRP concentration was measured, and individuals with hs-CRP <1.0 mg/l, and hs-CRP > 3.0 but <10.0 mg/l were compared. Results: Men and women with high hs-CRP had higher BMI, waist circumference, and triglyceride concentration, but lower HDL-cholesterol concentration. Adjusted for BMI, mean diet score was higher in the low hs-CRP group, both in men (10.8 +/- 3.6 vs. 9.9 +/- 3.8, p = 0.023) and women (12.7 +/- 3.4 vs. 11.6 +/- 3.5, p = 0.021). After further adjustments with potential confounding factors, the difference remained significant only in men. Conclusions: A diet that more closely adheres to the dietary recommendations is associated with lower hs-CRP in men. A prudent diet may help reduce systemic inflammation in type 1 diabetes. (C) 2017 Elsevier B.V. All rights reserved.
Subject: Adherence to dietary
recommendations
hs-CRP
Low-grade inflammation
Type 1 diabetes
TIME PHYSICAL-ACTIVITY
SYSTEMIC INFLAMMATION
CARDIOVASCULAR RISK
ELDERLY POPULATION
OXIDATIVE STRESS
GLYCEMIC CONTROL
FIBER INTAKE
DISEASE
WOMEN
NEPHROPATHY
3121 General medicine, internal medicine and other clinical medicine
Peer reviewed: Yes
Rights: unspecified
Usage restriction: openAccess
Self-archived version: publishedVersion


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