Breast Cancer Detection by Preoperative Imaging in Reduction Mammaplasty Patients : A Single Center Study of 918 Patients

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Merkkola-von Schantz , P A , Kauhanen , S M C , Jahkola , T A , Krogerus , L & Hukkinen , K S 2017 , ' Breast Cancer Detection by Preoperative Imaging in Reduction Mammaplasty Patients : A Single Center Study of 918 Patients ' , World Journal of Surgery , vol. 41 , no. 8 , pp. 2013-2019 . https://doi.org/10.1007/s00268-017-3920-z

Title: Breast Cancer Detection by Preoperative Imaging in Reduction Mammaplasty Patients : A Single Center Study of 918 Patients
Author: Merkkola-von Schantz, Paivi A.; Kauhanen, Susanna M. C.; Jahkola, Tiina A.; Krogerus, Leena; Hukkinen, Katja S.
Contributor organization: Plastiikkakirurgian yksikkö
HUS Musculoskeletal and Plastic Surgery
Clinicum
Department of Surgery
University of Helsinki
Medicum
Department of Pathology
Helsinki University Hospital Area
Department of Diagnostics and Therapeutics
HUS Medical Imaging Center
Date: 2017-08
Language: eng
Number of pages: 7
Belongs to series: World Journal of Surgery
ISSN: 0364-2313
DOI: https://doi.org/10.1007/s00268-017-3920-z
URI: http://hdl.handle.net/10138/237620
Abstract: Background The role of preoperative imaging and the usability of different imaging modalities is highly variable and controversial in reduction mammaplasty patients. Our study describes the imaging process in a single center in regard to modality selection, age and timing, and of the association between imaging and histopathological findings in reduction mammaplasty specimens. Methods Nine hundred eighteen women, who underwent reduction mammaplasty during 1.1.2007-31.12.2011, were retrospectively reviewed for demographics, preoperative imaging, further preoperative examinations, and pathology reports. Results Preoperative imaging had been conducted for 89.2% (n = 819) of the patients. In 49 (6.0%) patients, suspicious preoperative imaging led to further examinations revealing 2 high-risk lesions (atypical ductal hyperplasia (ADH), lobular carcinoma in situ (LCIS)), and 2 cancers preoperatively. Postoperatively abnormal histopathology specimens were revealed in 88 (10.4%) patients. The incidence of high-risk lesions was 5.5% (n = 47), and the incidence of cancer was 1.2% (n = 10). Preoperative imaging was normal (BI-RADS 1 and BI-RADS 2) in 80.8% of these patients. The sensitivity of the preoperative imaging for cancer detection was 20.0%, and the specificity was 100.0%. Conclusions Preoperative imaging and further examinations do not sufficiently detect malignant or cancer risk-increasing findings. Therefore, histopathological analysis of reduction mammaplasty specimens seems mandatory.
Subject: ATYPICAL HYPERPLASIA
CONSECUTIVE PATIENTS
CARCINOMA
WOMEN
RISK
MAMMOGRAPHY
SPECIMENS
DISEASE
SURGERY
MANAGEMENT
3126 Surgery, anesthesiology, intensive care, radiology
3122 Cancers
Peer reviewed: Yes
Usage restriction: openAccess
Self-archived version: publishedVersion


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