Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication
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Wolf , M , Korja , M , Karhu , R , Edgren , H , Kilpinen , S , Ojala , K , Mousses , S , Kallioniemi , A & Haapasalo , H 2010 , ' Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication ' , BMC Cancer , vol. 10 , no. 181 , pp. - . https://doi.org/10.1186/1471-2407-10-181
| Titel: | Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication |
| Författare: | Wolf, Maija; Korja, Miikka; Karhu, Ritva; Edgren, Henrik; Kilpinen, Sami; Ojala, Kalle; Mousses, Spyro; Kallioniemi, Anne; Haapasalo, Hannu |
| Upphovmannens organisation: | Institute for Molecular Medicine Finland Neurokirurgian yksikkö |
| Datum: | 2010 |
| Språk: | eng |
| Sidantal: | 13 |
| Tillhör serie: | BMC Cancer |
| ISSN: | 1471-2407 |
| DOI: | https://doi.org/10.1186/1471-2407-10-181 |
| Permanenta länken (URI): | http://hdl.handle.net/10138/23854 |
| Abstrakt: | Neuroblastoma has successfully served as a model system for the identification of neuroectoderm-derived oncogenes. However, in spite of various efforts, only a few clinically useful prognostic markers have been found. Here, we present a framework, which integrates DNA, RNA and tissue data to identify and prioritize genetic events that represent clinically relevant new therapeutic targets and prognostic biomarkers for neuroblastoma. |
| Subject: |
COMPARATIVE GENOMIC HYBRIDIZATION
IN-SITU HYBRIDIZATION MYCN-AMPLIFICATION COPY NUMBER SMAC/DIABLO EXPRESSION OVEREXPRESSED GENES CERVICAL-CANCER DOWN-REGULATION DNA IDENTIFICATION 318 Medical biotechnology |
| Referentgranskad: | Ja |
| Användningsbegränsning: | openAccess |
| Parallelpublicerad version: | publishedVersion |
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