Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication

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dc.contributor.author Wolf, Maija
dc.contributor.author Korja, Miikka
dc.contributor.author Karhu, Ritva
dc.contributor.author Edgren, Henrik
dc.contributor.author Kilpinen, Sami
dc.contributor.author Ojala, Kalle
dc.contributor.author Mousses, Spyro
dc.contributor.author Kallioniemi, Anne
dc.contributor.author Haapasalo, Hannu
dc.date.accessioned 2010-12-08T13:59:00Z
dc.date.available 2010-12-08T13:59:00Z
dc.date.issued 2010
dc.identifier.citation Wolf , M , Korja , M , Karhu , R , Edgren , H , Kilpinen , S , Ojala , K , Mousses , S , Kallioniemi , A & Haapasalo , H 2010 , ' Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication ' , BMC Cancer , vol. 10 , no. 181 , pp. - . https://doi.org/10.1186/1471-2407-10-181
dc.identifier.other PURE: 9484021
dc.identifier.other PURE UUID: 34ec285c-abd4-464c-9c35-3f876bdc5b4f
dc.identifier.other WOS: 000277804600001
dc.identifier.other Scopus: 77951872238
dc.identifier.other ORCID: /0000-0002-4463-6954/work/58742427
dc.identifier.uri http://hdl.handle.net/10138/23854
dc.description.abstract Neuroblastoma has successfully served as a model system for the identification of neuroectoderm-derived oncogenes. However, in spite of various efforts, only a few clinically useful prognostic markers have been found. Here, we present a framework, which integrates DNA, RNA and tissue data to identify and prioritize genetic events that represent clinically relevant new therapeutic targets and prognostic biomarkers for neuroblastoma. en
dc.format.extent 13
dc.language.iso eng
dc.relation.ispartof BMC Cancer
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject COMPARATIVE GENOMIC HYBRIDIZATION
dc.subject IN-SITU HYBRIDIZATION
dc.subject MYCN-AMPLIFICATION
dc.subject COPY NUMBER
dc.subject SMAC/DIABLO EXPRESSION
dc.subject OVEREXPRESSED GENES
dc.subject CERVICAL-CANCER
dc.subject DOWN-REGULATION
dc.subject DNA
dc.subject IDENTIFICATION
dc.subject 318 Medical biotechnology
dc.title Array-based gene expression, CGH and tissue data defines a 12q24 gain in neuroblastic tumors with prognostic implication en
dc.type Article
dc.contributor.organization Institute for Molecular Medicine Finland
dc.contributor.organization Neurokirurgian yksikkö
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1186/1471-2407-10-181
dc.relation.issn 1471-2407
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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