Objectively measured physical activity profile and cognition in Finnish elderly twins

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http://hdl.handle.net/10138/238888

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Iso-Markku , P , Waller , K , Vuoksimaa , E , Vähä-Ypyä , H , Lindgren , N , Heikkilä , K , Sievänen , H , Rinne , J , Kaprio , J & Kujala , U M 2018 , ' Objectively measured physical activity profile and cognition in Finnish elderly twins ' , Alzheimer's & Dementia: Translational Research & Clinical Interventions , vol. 4 , pp. 263-271 . https://doi.org/10.1016/j.trci.2018.06.007

Title: Objectively measured physical activity profile and cognition in Finnish elderly twins
Author: Iso-Markku, Paula; Waller, Katja; Vuoksimaa, Eero; Vähä-Ypyä, Henri; Lindgren, Noora; Heikkilä, Kauko; Sievänen, Harri; Rinne, Juha; Kaprio, Jaakko; Kujala, Urho M.
Contributor: University of Helsinki, HUS Medical Imaging Center
University of Helsinki, Institute for Molecular Medicine Finland
University of Helsinki, Department of Public Health
University of Helsinki, Institute for Molecular Medicine Finland
Date: 2018-07-14
Language: eng
Number of pages: 9
Belongs to series: Alzheimer's & Dementia: Translational Research & Clinical Interventions
ISSN: 2352-8737
URI: http://hdl.handle.net/10138/238888
Abstract: Introduction We studied whether objectively measured physical activity (PA) and sedentary behavior (SB) are associated with cognition in Finnish elderly twins. Methods This cross-sectional study comprised twins born in Finland from 1940 to 1944 in the Older Finnish Twin Cohort (mean age, 72.9 years; 726 persons). From 2014 to 2016, cognition was assessed with a validated telephonic interview, whereas PA was measured with a waist-worn accelerometer. Results In between-family models, SB and light physical activity had significant linear associations with cognition after adjusting for age, sex, wearing time, education level, body mass index, and living condition (SB: β-estimate, −0.21 [95% confidence intervals, −0.42 to −0.003]; light physical activity: β-estimate, 0.30 [95% confidence intervals, 0.02–0.58]). In within-family models, there were no significant linear associations between objectively measured PA and cognition. Discussion Objectively measured light physical activity and SB are associated with cognition in Finnish twins in their seventies, but the associations were attributable to genetic and environmental selection.
Subject: Cognition
Physical activity
Twins
Accelerometry
Dementia
Genetics
Exercise
Actigraphy
Sedentary behavior
Aged
3124 Neurology and psychiatry
315 Sport and fitness sciences
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