PANNZER2 : a rapid functional annotation web server

Show full item record



Permalink

http://hdl.handle.net/10138/243084

Citation

Törönen , P , Medlar , A & Holm , L 2018 , ' PANNZER2 : a rapid functional annotation web server ' , Nucleic Acids Research , vol. 46 , no. W1 , pp. W84-W88 . https://doi.org/10.1093/nar/gky350

Title: PANNZER2 : a rapid functional annotation web server
Author: Törönen, Petri; Medlar, Alan; Holm, Liisa
Contributor: University of Helsinki, Institute of Biotechnology
University of Helsinki, Computational genomics
University of Helsinki, Organismal and Evolutionary Biology Research Programme
Date: 2018-07-02
Language: eng
Number of pages: 5
Belongs to series: Nucleic Acids Research
ISSN: 0305-1048
URI: http://hdl.handle.net/10138/243084
Abstract: The unprecedented growth of high-throughput sequencing has led to an ever-widening annotation gap in protein databases. While computational prediction methods are available to make up the shortfall, a majority of public web servers are hindered by practical limitations and poor performance. Here, we introduce PANNZER2 (Protein ANNotation with ZscoRE), a fast functional annotation web server that provides both Gene Ontology (GO) annotations and free text description predictions. PANNZER2 uses SANSparallel to perform high-performance homology searches, making bulk annotation based on sequence similarity practical. PANNZER2 can output GO annotations from multiple scoring functions, enabling users to see which predictions are robust across predictors. Finally, PANNZER2 predictions scored within the top 10 methods for molecular function and biological process in the CAFA2 NK-full benchmark. The PANNZER2 web server is updated on a monthly schedule and is accessible at http://ekhidna2.biocenter.helsinki.fi/sanspanz/. The source code is available under the GNU Public Licence v3.
Subject: GENE ONTOLOGY
PROTEIN
TOOL
VISUALIZATION
ASSIGNMENTS
UNIPROT
1182 Biochemistry, cell and molecular biology
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
gky350.pdf 261.7Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record