Type 2 diabetic patients on renal replacement therapy : Probability to receive renal transplantation and survival after transplantation

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Kervinen , M H , Lehto , S , Helve , J , Grönhagen-Riska , C & Finne , P 2018 , ' Type 2 diabetic patients on renal replacement therapy : Probability to receive renal transplantation and survival after transplantation ' , PLoS One , vol. 13 , no. 8 , 0201478 . https://doi.org/10.1371/journal.pone.0201478

Title: Type 2 diabetic patients on renal replacement therapy : Probability to receive renal transplantation and survival after transplantation
Author: Kervinen, Marjo H.; Lehto, Seppo; Helve, Jaakko; Grönhagen-Riska, Carola; Finne, Patrik
Contributor: University of Helsinki, Department of Medicine
University of Helsinki, Clinicum
University of Helsinki, Faculty of Medicine
Date: 2018-08-15
Language: eng
Number of pages: 12
Belongs to series: PLoS One
ISSN: 1932-6203
URI: http://hdl.handle.net/10138/243579
Abstract: Background Type 2 diabetic (T2DM) patients on renal replacement therapy (RRT) seldom receive a kidney transplant, which is partly due to age and comorbidities. Adjusting for case mix, we investigated whether T2DM patients have equal opportunity for renal transplantation compared to other patients on dialysis, and whether survival after transplantation is comparable. Methods Patients who entered RRT in Finland in 2000-2010 (n = 5419) were identified from the Finnish Registry for Kidney Diseases and followed until the end of 2012. Of these, 20% had T2DM, 14% type 1 diabetes (T1 DM) and 66% other than diabetes as the cause of ESRD. Uni-/multivariate survival analysis techniques were employed to assess the probability of kidney transplantation after the start of dialysis and survival after transplantation. Results T2DM patients had a relative probability of renal transplantation of 0.18 (95% CI 0.15-0.22, P Conclusions T2DM patients had a considerably lower probability of receiving a kidney transplant, which could not be fully explained by differences in the patient characteristics. Survival within 5 years after transplantation is comparably good in T2DM patients.
Subject: KIDNEY-TRANSPLANTATION
WAITING-LIST
OUTCOMES
RISK
MANAGEMENT
DISEASE
PEOPLE
ACCESS
COHORT
OLDER
3121 General medicine, internal medicine and other clinical medicine
3126 Surgery, anesthesiology, intensive care, radiology
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