Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe : Results from the EPIC prospective cohort study

Show full item record



Permalink

http://hdl.handle.net/10138/250869

Citation

Deschasaux , M , Huybrechts , I , Murphy , N , Julia , C , Hercberg , S , Srour , B , Kesse-Guyot , E , Latino-Martel , P , Biessy , C , Casagrande , C , Jenab , M , Ward , H , Weiderpass , E , Dahm , C C , Overvad , K , Kyro , C , Olsen , A , Affret , A , Boutron-Ruault , M-C , Mahamat-Saleh , Y , Kaaks , R , Kuehn , T , Boeing , H , Schwingshackl , L , Bamia , C , Peppa , E , Trichopoulou , A , Masala , G , Krogh , V , Panico , S , Tumino , R , Sacerdote , C , Buen-de-Mesquita , B , Peeters , P H , Hjartaker , A , Rylander , C , Skeie , G , Ramon Quiros , J , Jakszyn , P , Salamanca-Fernandez , E , Maria Huerta , J , Ardanaz , E , Amiano , P , Ericson , U , Sonestedt , E , Huseinovic , E , Johansson , I , Khaw , K-T , Wareham , N , Bradbury , K E , Perez-Cornago , A , Tsilidis , K K , Ferrari , P , Riboli , E , Gunter , M J & Touvier , M 2018 , ' Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe : Results from the EPIC prospective cohort study ' , PLoS Medicine , vol. 15 , no. 9 , 1002651 . https://doi.org/10.1371/journal.pmed.1002651

Title: Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe : Results from the EPIC prospective cohort study
Author: Deschasaux, Melanie; Huybrechts, Inge; Murphy, Neil; Julia, Chantal; Hercberg, Serge; Srour, Bernard; Kesse-Guyot, Emmanuelle; Latino-Martel, Paule; Biessy, Carine; Casagrande, Corinne; Jenab, Mazda; Ward, Heather; Weiderpass, Elisabete; Dahm, Christina C.; Overvad, Kim; Kyro, Cecilie; Olsen, Anja; Affret, Aurelie; Boutron-Ruault, Marie-Christine; Mahamat-Saleh, Yahya; Kaaks, Rudolf; Kuehn, Tilman; Boeing, Heiner; Schwingshackl, Lukas; Bamia, Christina; Peppa, Eleni; Trichopoulou, Antonia; Masala, Giovanna; Krogh, Vittorio; Panico, Salvatore; Tumino, Rosario; Sacerdote, Carlotta; Buen-de-Mesquita, Bas; Peeters, Petra H.; Hjartaker, Anette; Rylander, Charlotta; Skeie, Guri; Ramon Quiros, J.; Jakszyn, Paula; Salamanca-Fernandez, Elena; Maria Huerta, Jose; Ardanaz, Eva; Amiano, Pilar; Ericson, Ulrika; Sonestedt, Emily; Huseinovic, Ena; Johansson, Ingegerd; Khaw, Kay-Tee; Wareham, Nick; Bradbury, Kathryn E.; Perez-Cornago, Aurora; Tsilidis, Konstantinos K.; Ferrari, Pietro; Riboli, Elio; Gunter, Marc J.; Touvier, Mathilde
Other contributor: University of Helsinki, Department of Medical and Clinical Genetics


Date: 2018-09
Language: eng
Number of pages: 21
Belongs to series: PLoS Medicine
ISSN: 1549-1676
DOI: https://doi.org/10.1371/journal.pmed.1002651
URI: http://hdl.handle.net/10138/250869
Abstract: Background Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British Food Standards Agency (modified version) (FSAm-NPS). How the consumption of foods with high/low FSAm-NPS relates to cancer risk has been studied in national/regional cohorts but has not been characterized in diverse European populations. Methods and findings This prospective analysis included 471,495 adults from the European Prospective Investigation into Cancer and Nutrition (EPIC, 1992-2014, median follow-up: 15.3 y), among whom there were 49,794 incident cancer cases (main locations: breast, n = 12,063; prostate, n = 6,745; colon-rectum, n = 5,806). Usual food intakes were assessed with standardized country-specific diet assessment methods. The FSAm-NPS was calculated for each food/beverage using their 100-g content in energy, sugar, saturated fatty acid, sodium, fibres, proteins, and fruits/vegetables/legumes/nuts. The FSAm-NPS scores of all food items usually consumed by a participant were averaged to obtain the individual FSAm-NPS Dietary Index (DI) scores. Multi-adjusted Cox proportional hazards models were computed. A higher FSAm-NPS DI score, reflecting a lower nutritional quality of the food consumed, was associated with a higher risk of total cancer (HRQ5 versus (Q1) = 1.07; 95% CI 1.03-1.10, P-trend <0.001). Absolute cancer rates in those with high and low (quintiles 5 and 1) FSAm-NPS DI scores were 81.4 and 69.5 cases/10,000 person-years, respectively. Higher FSAm-NPS DI scores were specifically associated with higher risks of cancers of the colon-rectum, upper aerodigestive tract and stomach, lung for men, and liver and postmenopausal breast for women (all P <0.05). The main study limitation is that it was based on an observational cohort using self-reported dietary data obtained through a single baseline food frequency questionnaire; thus, exposure misclassification and residual confounding cannot be ruled out. Conclusions In this large multinational European cohort, the consumption of food products with a higher FSAm-NPS score (lower nutritional quality) was associated with a higher risk of cancer. This supports the relevance of the FSAm-NPS as underlying nutrient profiling system for front-of-pack nutrition labels, as well as for other public health nutritional measures.
Subject: CARDIOVASCULAR-DISEASE RISK
FRONT-OF-PACKAGE
DIETARY INDEX
PROSPECTIVE ASSOCIATION
SU.VI.MAX COHORT
FRENCH ADULTS
VALIDATION
DATABASE
PROJECT
FRANCE
3121 Internal medicine
Rights:


Files in this item

Total number of downloads: Loading...

Files Size Format View
journal.pmed.1002651.pdf 1.371Mb PDF View/Open

This item appears in the following Collection(s)

Show full item record