Association between diet and measures of arterial stiffness in type 1 diabetes - Focus on dietary patterns and macronutrient substitutions

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Finndiane Study Grp 2018 , ' Association between diet and measures of arterial stiffness in type 1 diabetes - Focus on dietary patterns and macronutrient substitutions ' , Nutrition, Metabolism and Cardiovascular Diseases , vol. 28 , no. 11 , pp. 1166-1172 . https://doi.org/10.1016/j.numecd.2018.07.003

Title: Association between diet and measures of arterial stiffness in type 1 diabetes - Focus on dietary patterns and macronutrient substitutions
Author: Finndiane Study Grp
Date: 2018-11
Language: eng
Number of pages: 7
Belongs to series: Nutrition, Metabolism and Cardiovascular Diseases
ISSN: 0939-4753
URI: http://hdl.handle.net/10138/267613
Abstract: Background and aims: Increased arterial stiffness contributes to diabetic vascular complications. We identified dietary factors related to arterial stiffness in individuals with type 1 diabetes, a population with high risk of cardiovascular disease. Methods and results: Altogether, 612 participants (40% men, mean +/- standard deviation age 45 +/- 13 years) completed a validated diet questionnaire and underwent measurements of arterial stiffness. Of these, 470 additionally completed a food record. Exploratory factor analysis was applied to identify dietary patterns from the diet questionnaires, and nutrient intakes were calculated from food record entries. Arterial stiffness was measured by applanation tonometry. Of the seven dietary factors formed, the factor scores of "Full-fat cheese and eggs" and "Sweet" patterns were negatively associated with measures of arterial stiffness. In the multivariable macronutrient substitution models, favouring carbohydrates over fats was associated with higher aortic mean arterial pressure and aortic pulse wave velocity. When carbohydrates were consumed in place of proteins, higher aortic pulse pressure, aortic mean arterial pressure, and augmentation index were recorded. Replacing energy from alcohol with proteins, was associated with lower aortic pulse pressure, aortic mean arterial pressure, and augmentation index. Relative distributions of dietary fatty acids were neutral with respect to the measures of arterial stiffness. Conclusion: The macronutrient distribution of the diet is likely to affect the resilience of the arteries. Our observations suggest that reducing energy intake from carbohydrates and alcohol may be beneficial. These observations, especially those dealing with dietary patterns, need to be confirmed in a longitudinal study. (C) 2018 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.
Subject: Arterial stiffness
Dietary patterns
Macronutrient substitution
Type 1 diabetes
CORONARY-HEART-DISEASE
ALL-CAUSE MORTALITY
CARDIOVASCULAR-DISEASE
BLOOD-PRESSURE
ENDOTHELIAL FUNCTION
RISK
METAANALYSIS
MEN
HEALTH
CONSUMPTION
3121 General medicine, internal medicine and other clinical medicine
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