Marked deterioration in the quality of life of patients with idiopathic pulmonary fibrosis during the last two years of life

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dc.contributor.author Rajala, K.
dc.contributor.author Lehto, J. T.
dc.contributor.author Sutinen, E.
dc.contributor.author Kautiainen, H.
dc.contributor.author Myllärniemi, M.
dc.contributor.author Saarto, T.
dc.date.accessioned 2018-11-29T11:28:01Z
dc.date.available 2018-11-29T11:28:01Z
dc.date.issued 2018-11-20
dc.identifier.citation Rajala , K , Lehto , J T , Sutinen , E , Kautiainen , H , Myllärniemi , M & Saarto , T 2018 , ' Marked deterioration in the quality of life of patients with idiopathic pulmonary fibrosis during the last two years of life ' , BMC Pulmonary Medicine , vol. 18 , 172 . https://doi.org/10.1186/s12890-018-0738-x
dc.identifier.other PURE: 119622948
dc.identifier.other PURE UUID: 56007d99-0622-4452-9bc1-1e44302ec6c3
dc.identifier.other WOS: 000450798800001
dc.identifier.other ORCID: /0000-0001-9343-0867/work/51327723
dc.identifier.other Scopus: 85056802994
dc.identifier.uri http://hdl.handle.net/10138/268055
dc.description.abstract BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic disease with a high symptom burden and poor survival that influences patients' health-related quality of life (HRQOL). We aimed to evaluate IPF patients' symptoms and HRQOL in a well-documented clinical cohort during their last two years of life.MethodsIn April 2015, we sent the Modified Medical Research Council Dyspnea Scale (MMRC), the modified Edmonton Symptom Assessment Scale (ESAS) and a self-rating HRQOL questionnaire (RAND-36) to 300 IPF patients, of which 247 (82%) responded. Thereafter, follow-up questionnaires were sent every six months for two years.ResultsNinety-two patients died by August 2017. Among these patients, HRQOL was found to be considerably low already two years before death. The most prominent declines in HRQOL occurred in physical function, vitality, emotional role and social functioning (p en
dc.format.extent 9
dc.language.iso eng
dc.relation.ispartof BMC Pulmonary Medicine
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Idiopathic pulmonary fibrosis
dc.subject Palliative care
dc.subject Health related quality of life
dc.subject Symptoms
dc.subject RANDOMIZED CONTROLLED-TRIAL
dc.subject LUNG-CANCER PATIENTS
dc.subject INTEGRATED PALLIATIVE CARE
dc.subject CLINICAL-PRACTICE
dc.subject FUNCTIONAL STATUS
dc.subject IPF REGISTRY
dc.subject DISEASE
dc.subject MANAGEMENT
dc.subject DYSPNEA
dc.subject COMORBIDITIES
dc.subject 3121 General medicine, internal medicine and other clinical medicine
dc.title Marked deterioration in the quality of life of patients with idiopathic pulmonary fibrosis during the last two years of life en
dc.type Article
dc.contributor.organization Department of Medicine
dc.contributor.organization Keuhkosairauksien yksikkö
dc.contributor.organization Clinicum
dc.contributor.organization University of Helsinki
dc.contributor.organization Department of Oncology
dc.contributor.organization HUS Heart and Lung Center
dc.contributor.organization HUS Comprehensive Cancer Center
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1186/s12890-018-0738-x
dc.relation.issn 1471-2466
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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