Factors determining level of hospital care and its association with outcome after resuscitation from pre-hospital pulseless electrical activity

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http://hdl.handle.net/10138/277460

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Saarinen , S , Salo , A , Boyd , J , Laukkanen-Nevala , P , Silfvast , C , Virkkunen , I & Silfvast , T 2018 , ' Factors determining level of hospital care and its association with outcome after resuscitation from pre-hospital pulseless electrical activity ' , Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine , vol. 26 , 98 . https://doi.org/10.1186/s13049-018-0568-0

Title: Factors determining level of hospital care and its association with outcome after resuscitation from pre-hospital pulseless electrical activity
Author: Saarinen, Sini; Salo, Ari; Boyd, James; Laukkanen-Nevala, Päivi; Silfvast, Catharina; Virkkunen, Ilkka; Silfvast, Tom
Contributor: University of Helsinki, HUS Emergency Medicine and Services
University of Helsinki, HUS Emergency Medicine and Services
University of Helsinki, Department of Diagnostics and Therapeutics
Date: 2018-11-19
Language: eng
Number of pages: 9
Belongs to series: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
ISSN: 1757-7241
URI: http://hdl.handle.net/10138/277460
Abstract: Patients resuscitated from out-of-hospital cardiac arrest (OHCA) with pulseless electrical activity (PEA) as initial cardiac rhythm are not always treated in intensive care units (ICUs): some are admitted to high dependency units with various level of care, others to ordinary wards. Aim of this study was to describe the factors determining level of hospital care after OHCA with PEA, post-resuscitation care and survival. Adult OHCA patients with PEA (n = 221), who were resuscitated in southern Finland between 2010 and 2013 were included, provided patient survived to hospital admission. The patients were divided into four groups according to the level of hospital care provided: ordinary ward and Level 1-3 ICUs. Differences in patient characteristics, post-resuscitation care and survival were compared between the groups. Most patients (62.4%) were treated at Level 2 ICUs. Longer time to ROSC and advanced age decreased admission rate to Level 2 or 3 post-resuscitation care, whereas good pre-arrest CPC (1-2) increased the admission rate to Level 2/3 ICUs independently. Treatment with targeted temperature management (TTM) (4.1%) or early coronary angiography (3.2%) were very rare. Prognostic decisions were made earlier in the lower treatment intensity groups (p <0.01). One-year survival rate was 24.0, 17.1% survived with good neurological outcome. Neurological outcome was better with more intensive care. After adjustment, level of care was not independent predictor for outcome: only return of spontaneous circulation (ROSC) time, cardiac arrest cause and pre-arrest performance affected independently to 1-year survival, age and ROSC for neurologic outcome. PEA are usually admitted to Level 2 ICUs for post-resuscitation care in the capital area of Finland. Age, ROSC and pre-arrest CPC were independent predictors for level of post-resuscitation care. TTM and early CAG were rare and provided only for Level 3 ICU patients. Prognostication was earlier in lower level of care units. Good neurologic survival was more common with more intensive level of post-resuscitation care. After adjustment, level of care was not independent predictor for survival or neurologic outcome: only ROSC, cardiac arrest cause and pre-arrest performance predicted 1-year survival; age and ROSC neurologic outcome.
Subject: Heart arrest
Cardiopulmonary resuscitation
Pulseless electrical activity
Post-resuscitation care
CARDIAC-ARREST
THERAPEUTIC HYPOTHERMIA
COUNCIL GUIDELINES
ADVISORY STATEMENT
EUROPEAN-SOCIETY
ELDERLY-PATIENTS
TASK-FORCE
SURVIVAL
RHYTHM
UNIT
3126 Surgery, anesthesiology, intensive care, radiology
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