Blinded Analysis of an Exercise ECG Database Using High Frequency QRS Analysis

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Omer , N , Granot , Y , Kähönen , M , Lehtinen , R , Nieminen , T , Nikus , K , Lehtimäki , T , Viik , J & Abboud , S 2017 , Blinded Analysis of an Exercise ECG Database Using High Frequency QRS Analysis . in 2017 COMPUTING IN CARDIOLOGY (CINC) . Computing in Cardiology Series , IEEE Computer Society , 44th Computing in Cardiology Conference (CinC) , Rennes , France , 24/09/2017 .

Title: Blinded Analysis of an Exercise ECG Database Using High Frequency QRS Analysis
Author: Omer, Noam; Granot, Yair; Kähönen, Mika; Lehtinen, Rami; Nieminen, Tuomo; Nikus, Kjell; Lehtimäki, Terho; Viik, Jari; Abboud, Shimon
Contributor organization: Department of Medicine
Kardiologian yksikkö
HUS Internal Medicine and Rehabilitation
Publisher: IEEE Computer Society
Date: 2017
Language: eng
Number of pages: 4
Belongs to series: 2017 COMPUTING IN CARDIOLOGY (CINC)
Belongs to series: Computing in Cardiology Series
ISSN: 0276-6574
Abstract: High frequency QRS (HFQRS) analysis was shown to be more accurate than ST changes in detecting stress induced ischemia in designed clinical studies. Since it utilizes energy extracted from the frequency band of 150250 Hz, HFQRS analysis is performed with high end electrocardiographs which are equipped with adequate hardware. In this study, we aim to examine whether it is possible to perform the HFQRS analysis using ECG data acquired by a 500 Hz commercial electrocardiograph and also to assess the clinical performance of such analysis. One hundred and thirty two ECG records of bicycle exercise tests were obtained from the FINCAVAS database. Fifteen records with a wide QRS duration and 28 patients who have not reached their target heart rate were excluded. HFQRS and computerized ST-segment analyses were performed for the remaining 89 records in a blinded fashion. Three records were excluded due to excessive high frequency noise. Accordingly, the group of records with a definite HFQRS interpretation included 57 patients without stenosis and 29 patients who had > 75% stenosis. Angiography, was used as gold standard. The clinical performance of both methods were assessed. The HFQRS has statistically significant higher sensitivity of 86% comparing to the 41% of the ST (p <0.005) with a statistically insignificant difference in specificity of 68% vs. 67% for the HFQRS and the ST respectively (p = 0.84). This analysis demonstrated that HFQRS analysis may be applied for ECG data acquired by standard 500 Hz electrocardiographs and demonstrates its potential in diagnosing stress induced ischemia.
3121 General medicine, internal medicine and other clinical medicine
Peer reviewed: Yes
Usage restriction: openAccess
Self-archived version: publishedVersion

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