Arabidopsis GRI is involved in the regulation of cell death induced by extracellular ROS

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http://hdl.handle.net/10138/28518

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Wrzaczek , M , Brosche , M , Kollist , H & Kangasjärvi , J 2009 , ' Arabidopsis GRI is involved in the regulation of cell death induced by extracellular ROS ' , Proceedings of the National Academy of Sciences of the United States of America , vol. 106 , no. 13 , pp. 5412-5417 . https://doi.org/10.1073/pnas.0808980106

Title: Arabidopsis GRI is involved in the regulation of cell death induced by extracellular ROS
Author: Wrzaczek, Michael; Brosche, Mikael; Kollist, Hannes; Kangasjärvi, Jaakko
Contributor: University of Helsinki, Receptor-Ligand Signaling Group
University of Helsinki, Plant Biology
University of Helsinki, Plant Biology
Date: 2009
Language: eng
Number of pages: 6
Belongs to series: Proceedings of the National Academy of Sciences of the United States of America
ISSN: 0027-8424
URI: http://hdl.handle.net/10138/28518
Abstract: Reactive oxygen species (ROS) have important functions in plant stress responses and development. In plants, ozone and pathogen infection induce an extracellular oxidative burst that is involved in the regulation of cell death. However, very little is known about how plants can perceive ROS and regulate the initiation and the containment of cell death. We have identified an Arabidopsis thaliana protein, GRIM REAPER (GRI), that is involved in the regulation of cell death induced by extracellular ROS. Plants with an insertion in GRI display an ozone-sensitive phenotype. GRI is an Arabidopsis ortholog of the tobacco flower-specific Stig1 gene. The GRI protein appears to be processed in leaves with a release of an N-terminal fragment of the protein. Infiltration of the N-terminal fragment of the GRI protein into leaves caused cell death in a superoxide-and salicylic acid-dependent manner. Analysis of the extracellular GRI protein yields information on how plants can initiate ROS-induced cell death during stress response and development.
Subject: 311 Basic medicine
318 Medical biotechnology
411 Agriculture and forestry
118 Biological sciences
219 Environmental biotechnology
519 Social and economic geography
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