Experimental transmission of Zika virus by Aedes japonicus japonicus from southwestern Germany

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dc.contributor.author Jansen, Stephanie
dc.contributor.author Heitmann, Anna
dc.contributor.author Lühken, Renke
dc.contributor.author Jöst, Hanna
dc.contributor.author Helms, Michelle
dc.contributor.author Vapalahti, Olli
dc.contributor.author Schmidt-Chanasit, Jonas
dc.contributor.author Tannich, Egbert
dc.date.accessioned 2019-01-03T14:18:02Z
dc.date.available 2019-01-03T14:18:02Z
dc.date.issued 2018-11-28
dc.identifier.citation Jansen , S , Heitmann , A , Lühken , R , Jöst , H , Helms , M , Vapalahti , O , Schmidt-Chanasit , J & Tannich , E 2018 , ' Experimental transmission of Zika virus by Aedes japonicus japonicus from southwestern Germany ' , Emerging microbes & infections , vol. 7 , 192 . https://doi.org/10.1038/s41426-018-0195-x
dc.identifier.other PURE: 120673898
dc.identifier.other PURE UUID: bfef9717-4ea1-4648-b096-a9594e83ff9d
dc.identifier.other WOS: 000452311600005
dc.identifier.other Scopus: 85057280561
dc.identifier.other ORCID: /0000-0003-2270-6824/work/52396062
dc.identifier.uri http://hdl.handle.net/10138/285689
dc.description.abstract The invasive mosquito species Aedes japonicus japonicus (Ae. japonicus) is widely distributed in Central Europe and is a known vector of various arboviruses in the laboratory, including flaviviruses such as Japanese Encephalitis virus or West Nile virus. However, the vector competence of Ae. japonicus for the recently emerging Zika virus (ZIKV) has not been determined. Therefore, field-caught Ae. japonicus from Germany were orally infected with ZIKV and incubated at 21, 24, or 27 degrees C to evaluate the vector competence under climate conditions representative of the temperate regions (21 degrees C) in the species' main distribution area in Europe and of Mediterranean regions (27 degrees C). Aedes japonicus was susceptible to ZIKV at all temperatures, showing infection rates between 10.0% (21 degrees C) and 66.7% (27 degrees C). However, virus transmission was detected exclusively at 27 degrees C with a transmission rate of 14.3% and a transmission efficiency of 9.5%. Taking into account the present distribution of Ae. japonicus in the temperate regions of Central Europe, the risk of ZIKV transmission by the studied Ae. japonicus population in Central Europe has to be considered as low. Nevertheless, due to the species' vector competence for ZIKV and other mosquito-borne viruses, in combination with the possibility of further spread to Mediterranean regions, Ae. japonicus must be kept in mind as a potential vector of pathogens inside and outside of Europe. en
dc.format.extent 6
dc.language.iso eng
dc.relation.ispartof Emerging microbes & infections
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject DIPTERA-CULICIDAE
dc.subject ENCEPHALITIS-VIRUS
dc.subject VECTOR COMPETENCE
dc.subject 1ST RECORD
dc.subject MOSQUITOS
dc.subject IDENTIFICATION
dc.subject INFECTION
dc.subject KOREICUS
dc.subject 3111 Biomedicine
dc.title Experimental transmission of Zika virus by Aedes japonicus japonicus from southwestern Germany en
dc.type Article
dc.contributor.organization Olli Pekka Vapalahti / Principal Investigator
dc.contributor.organization Viral Zoonosis Research Unit
dc.contributor.organization Department of Virology
dc.contributor.organization University of Helsinki
dc.contributor.organization Clinicum
dc.contributor.organization Medicum
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1038/s41426-018-0195-x
dc.relation.issn 2222-1751
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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