Factors associated with acute kidney injury in the Helsinki Burn Centre in 2006-2015

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dc.contributor.author Rakkolainen, I.
dc.contributor.author Lindbohm, J. V.
dc.contributor.author Vuola, J.
dc.date.accessioned 2019-01-07T14:27:01Z
dc.date.available 2019-01-07T14:27:01Z
dc.date.issued 2018-12-13
dc.identifier.citation Rakkolainen , I , Lindbohm , J V & Vuola , J 2018 , ' Factors associated with acute kidney injury in the Helsinki Burn Centre in 2006-2015 ' , Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine , vol. 26 , 105 . https://doi.org/10.1186/s13049-018-0573-3
dc.identifier.other PURE: 120805217
dc.identifier.other PURE UUID: ba11a18c-af50-459a-9794-86f7d877b12b
dc.identifier.other WOS: 000453321900001
dc.identifier.other Scopus: 85058490667
dc.identifier.other ORCID: /0000-0002-9820-2692/work/52399889
dc.identifier.uri http://hdl.handle.net/10138/287690
dc.description.abstract BackgroundAcute kidney injury (AKI) is a common complication in severe burns and can lead to significantly poorer outcomes. Although the prognosis has improved in recent decades, the mortality of AKI remains considerable. We investigated the factors that increase the risk of AKI and death after severe burn injury.MethodsIntensive care patients with 20% burned total body surface area (TBSA%) between January 2006 and December 2015 treated in Helsinki Burn Centre were enrolled retrospectively. Patients who arrived >36h after burn injury or died 80. Multivariate logistic regression model detected age, TBSA%, sepsis, and rhabdomyolysis as independent risk factors for AKI. Age (per 10yrs. OR 1.99), TBSA% (per 10% OR 1.64), and AKI predicted mortality during hospital stay; AKI had an odds ratio of (OR) of 5.97 (95% confidence interval [CI] 2.2-16.2).ConclusionsAge, TBSA%, and AKI were the strongest independent factors in predicting outcome in severe burns. Even a major burn (>50% TBSA) has a relatively good prognosis without simultaneous AKI. Prognosis is poorer even in minor burns for patients with AKI. en
dc.format.extent 10
dc.language.iso eng
dc.relation.ispartof Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine
dc.rights cc_by
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Burn injury
dc.subject Acute kidney injury
dc.subject Renal replacement therapy
dc.subject MORTALITY
dc.subject CARE
dc.subject PREDICTION
dc.subject MORBIDITY
dc.subject RISK
dc.subject 3126 Surgery, anesthesiology, intensive care, radiology
dc.title Factors associated with acute kidney injury in the Helsinki Burn Centre in 2006-2015 en
dc.type Article
dc.contributor.organization Department of Public Health
dc.contributor.organization Clinicum
dc.contributor.organization University of Helsinki
dc.contributor.organization Plastiikkakirurgian yksikkö
dc.contributor.organization HUS Musculoskeletal and Plastic Surgery
dc.contributor.organization HUS Neurocenter
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1186/s13049-018-0573-3
dc.relation.issn 1757-7241
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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