Influence of mouthwashes on extended exhaled nitric oxide (FENO) analysis

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http://hdl.handle.net/10138/288218

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Lassmann-Klee , P G , Lehtimäki , L , Lindholm , T , Malmberg , L P , Sovijärvi , A & Piirilä , P 2018 , ' Influence of mouthwashes on extended exhaled nitric oxide ( F ENO ) analysis ' , Scandinavian Journal of Clinical and Laboratory Investigation , vol. 78 , no. 6 , pp. 450-455 . https://doi.org/10.1080/00365513.2018.1497802

Title: Influence of mouthwashes on extended exhaled nitric oxide (FENO) analysis
Author: Lassmann-Klee, Paul Guenther; Lehtimäki, Lauri; Lindholm, Tuula; Malmberg, L. Pekka; Sovijärvi, Anssi; Piirilä, Päivi
Contributor: University of Helsinki, Department of Diagnostics and Therapeutics
University of Helsinki, Department of Dermatology, Allergology and Venereology
University of Helsinki, Department of Diagnostics and Therapeutics
University of Helsinki, Clinicum
Date: 2018-10-22
Language: eng
Number of pages: 6
Belongs to series: Scandinavian Journal of Clinical and Laboratory Investigation
ISSN: 0036-5513
URI: http://hdl.handle.net/10138/288218
Abstract: Fractional exhaled nitric oxide (F-ENO) is used to assess eosinophilic inflammation of the airways. F-ENO values are influenced by the expiratory flow rate and orally produced NO. We measured F-ENO at four different expiratory flow levels after two different mouthwashes: tap water and carbonated water. Further, we compared the alveolar NO concentration (C-ANO), maximum airway NO flux (J(awNO)) and airway NO diffusion (D-awNO) after these two mouthwashes. F-ENO was measured in 30 volunteers (healthy or asthmatic) with a chemiluminescence NO-analyser at flow rates of 30, 50, 100 and 300mL/s. A mouthwash was performed before the measurement at every flow rate. The carbonated water mouthwash significantly reduced F-ENO compared to the tap water mouthwash at all expiratory flows: 50mL/s (p
Subject: Nitric oxide (NO)
alveolar NO concentration (C-ANO)
asthma
fractional exhaled nitric oxide (F-ENO)
maximum airway NO flux (J(awNO))
mouthwashes
carbonated water
inflammation
respiratory system
exhalation
airway obstruction
oropharynx
ALVEOLAR
ASTHMA
NASAL
FENO
SPIROMETRY
REDUCTION
DIFFUSION
NITRATE
MOUTH
AIR
3121 General medicine, internal medicine and other clinical medicine
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