Intellectual disability in patients with epilepsy with eyelid myoclonias

Show simple item record

dc.contributor University of Helsinki, HYKS erva en
dc.contributor University of Helsinki, HYKS erva en
dc.contributor.author Arvio, Maria
dc.contributor.author Sauna-aho, Oili
dc.contributor.author Nyrke, Timo
dc.contributor.author Bjelogrlic-Laakso, Nina
dc.date.accessioned 2019-01-11T10:42:01Z
dc.date.available 2019-01-11T10:42:01Z
dc.date.issued 2018-05-21
dc.identifier.citation Arvio , M , Sauna-aho , O , Nyrke , T & Bjelogrlic-Laakso , N 2018 , ' Intellectual disability in patients with epilepsy with eyelid myoclonias ' SAGE open medical case reports , vol. 6 , 2050313X18777951 . https://doi.org/10.1177/2050313X18777951 en
dc.identifier.issn 2050-313X
dc.identifier.other PURE: 115065695
dc.identifier.other PURE UUID: 1ede6bba-2636-4e70-90be-e0a73bf8d0a9
dc.identifier.other WOS: 000432889900001
dc.identifier.uri http://hdl.handle.net/10138/290320
dc.description.abstract We describe here the clinical outcome of four women with epilepsy with eyelid myoclonia (aged 21-53years). All patients had an uneventful early history, normal physical growth and appearance and no comorbid sensory or motor disability and normal brain magnetic resonance imaging finding. Two women were moderately and one mildly intellectually disabled and one showed a low-average intelligence. The overall well-being of the patients was hampered by psychiatric or various somatic comorbidities and related psychosocial problems. The three women with an intellectual disability had been treated with narrow-spectrum antiepileptic drugs and one also with vigabatrin during childhood and adolescence. The patient with a low-average intelligence had been on broad-spectrum antiepileptic medication (i.e. valproate and ethosuximide) since the epilepsy diagnosis but she has had compliance problems. Based on these cases, the cognitive deficits in patients with epilepsy with eyelid myoclonia may occur more commonly than what has been thought hitherto. We discuss the role of narrow-spectrum antiepileptic drugs as a contributing factor to poor seizure control and an impaired intelligence. en
dc.format.extent 4
dc.language.iso eng
dc.relation.ispartof SAGE open medical case reports
dc.rights en
dc.subject Epilepsy with eyelid myoclonias en
dc.subject Jeavons syndrome en
dc.subject eyelid myoclonia with absences en
dc.subject intellectual disability en
dc.subject 3112 Neurosciences en
dc.subject 3124 Neurology and psychiatry en
dc.title Intellectual disability in patients with epilepsy with eyelid myoclonias en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.1177/2050313X18777951
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
dc.contributor.pbl

Files in this item

Total number of downloads: Loading...

Files Size Format View
10.1177_2050313X18777951.pdf 366.9Kb PDF View/Open

This item appears in the following Collection(s)

Show simple item record