Lower urinary tract symptoms and sexual functions after endorectal pull-through for Hirschsprung disease : controlled long-term outcomes

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http://hdl.handle.net/10138/297847

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Neuvonen , M , Kyrklund , K , Taskinen , S , Koivusalo , A , Rintala , R J & Pakarinen , M P 2017 , ' Lower urinary tract symptoms and sexual functions after endorectal pull-through for Hirschsprung disease : controlled long-term outcomes ' , Journal of Pediatric Surgery , vol. 52 , no. 8 , pp. 1296-1301 . https://doi.org/10.1016/j.jpedsurg.2017.02.013

Title: Lower urinary tract symptoms and sexual functions after endorectal pull-through for Hirschsprung disease : controlled long-term outcomes
Author: Neuvonen, Malla; Kyrklund, Kristiina; Taskinen, Seppo; Koivusalo, Antti; Rintala, Risto J.; Pakarinen, Mikko P.
Contributor: University of Helsinki, Children's Hospital
University of Helsinki, Children's Hospital
University of Helsinki, Lastenkirurgian yksikkö
University of Helsinki, University of Helsinki
University of Helsinki, Lastenkirurgian yksikkö
Date: 2017-08
Language: eng
Number of pages: 6
Belongs to series: Journal of Pediatric Surgery
ISSN: 0022-3468
URI: http://hdl.handle.net/10138/297847
Abstract: Background/purpose: To define the prevalence of lower urinary tract symptoms (LUTS) and outcomes for sexual function after endorectal pull-through (EPT) for Hirschsprung disease (HD) compared to controls. To date, similar controlled studies are lacking. Methods: Patients aged = 4 years (n= 123) operated on forHDat our center between 1987 and 2011were invited to answer questionnaires on LUTS and sexual function (aged = 16 years). Patients with an intellectual disability and patients with a definitive endostomy were excluded. Patients were matched to three controls and also invited to a clinical follow-up for urological investigations including urine flow measurement, renal tract ultrasound, and urinalysis. Results: Altogether, 59 responses concerning LUTS and 24 responses concerning sexual functions were analyzed. No significant differences were demonstrated in the overall prevalence of LUTS between patients (67%) and controls (80%), nor in the prevalence of frequent LUTS (14% vs. 16%; P = NS for both). One patient (2%) had a urethral stricture after laparotomy-assisted EPT. Male patients reported sexual satisfaction and erectile function similar to controls (P N 0.10). Female patients were currently less in stable relationships compared to controls (25% vs. 83%, P= 0.005). Conclusions: Our results support the safety of EPT in patientswith HDwith regard to preservation of the integrity and functioning of the genitourinary tract. (C) 2017 Elsevier Inc. All rights reserved.
Subject: LUTS
Sexual function
Hirschsprung's disease
Endorectal pull-through
QUALITY-OF-LIFE
BOWEL FUNCTION
SAGITTAL ANORECTOPLASTY
FOLLOW-UP
CHILDREN
DEPRESSION
EXPERIENCE
SURGERY
MULTICENTER
ADOLESCENTS
3123 Gynaecology and paediatrics
3126 Surgery, anesthesiology, intensive care, radiology
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