Genomes of viral isolates derived from different mosquitos species

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http://hdl.handle.net/10138/298155

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Sadeghi , M , Popov , V , Guzman , H , Phan , T G , Vasilakis , N , Tesh , R & Delwart , E 2017 , ' Genomes of viral isolates derived from different mosquitos species ' , Virus Research , vol. 242 , pp. 49-57 . https://doi.org/10.1016/j.virusres.2017.08.012

Titel: Genomes of viral isolates derived from different mosquitos species
Författare: Sadeghi, Mohammadreza; Popov, Vsevolod; Guzman, Hilda; Phan, Tung Gia; Vasilakis, Nikos; Tesh, Robert; Delwart, Eric
Upphovmannens organisation: Department of Virology
Medicum
Datum: 2017-10-15
Språk: eng
Sidantal: 9
Tillhör serie: Virus Research
ISSN: 0168-1702
DOI: https://doi.org/10.1016/j.virusres.2017.08.012
Permanenta länken (URI): http://hdl.handle.net/10138/298155
Abstrakt: Eleven viral isolates derived mostly in albopictus C6/36 cells from mosquito pools collected in Southeast Asia and the Americas between 1966 and 2014 contained particles with electron microscopy morphology typical of reoviruses. Metagenomics analysis yielded the near complete genomes of three novel reoviruses, Big Cypress orbivirus, Ninarumi virus, and High Island virus and a new tetravirus, Sarawak virus. Strains of previously characterized Sathuvarachi, Yunnan, Banna and Parry's Lagoon viruses (Reoviridae), Bontang virus (Mesoniviridae), and Culex theileri flavivirus (Flaviviridae) were also characterized. The availability of these mosquito virus genomes will facilitate their detection by metagenomics or PCR to better determine their geographic range, extent of host tropism, and possible association with arthropod or vertebrate disease.
Subject: Metagenomics
Reoviridae
Viral discovery
Mosquito
Deep sequencing
Orbivirus
OPEROPHTERA-BRUMATA LEPIDOPTERA
SEQUENCE-ANALYSIS
PROVIDENCE-VIRUS
HOST-RANGE
CELL-LINE
ORBIVIRUS
CULEX
GEOMETRIDAE
REOVIRIDAE
VIROME
3111 Biomedicine
Referentgranskad: Ja
Användningsbegränsning: openAccess
Parallelpublicerad version: publishedVersion


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