eUTOPIA: solUTion for Omics data PreprocessIng and Analysis

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dc.contributor.author Marwah, Veer S
dc.contributor.author Scala, Giovanni
dc.contributor.author Kinaret, Pia A S
dc.contributor.author Serra, Angela
dc.contributor.author Alenius, Harri
dc.contributor.author Fortino, Vittorio
dc.contributor.author Greco, Dario
dc.date.accessioned 2019-02-03T04:18:56Z
dc.date.available 2019-02-03T04:18:56Z
dc.date.issued 2019-01-29
dc.identifier.citation Source Code for Biology and Medicine. 2019 Jan 29;14(1):1
dc.identifier.uri http://hdl.handle.net/10138/298630
dc.description.abstract Abstract Background Application of microarrays in omics technologies enables quantification of many biomolecules simultaneously. It is widely applied to observe the positive or negative effect on biomolecule activity in perturbed versus the steady state by quantitative comparison. Community resources, such as Bioconductor and CRAN, host tools based on R language that have become standard for high-throughput analytics. However, application of these tools is technically challenging for generic users and require specific computational skills. There is a need for intuitive and easy-to-use platform to process omics data, visualize, and interpret results. Results We propose an integrated software solution, eUTOPIA, that implements a set of essential processing steps as a guided workflow presented to the user as an R Shiny application. Conclusions eUTOPIA allows researchers to perform preprocessing and analysis of microarray data via a simple and intuitive graphical interface while using state of the art methods.
dc.publisher BioMed Central
dc.subject Transcriptomics analysis
dc.subject Microarray
dc.subject Gene expression
dc.subject R shiny
dc.title eUTOPIA: solUTion for Omics data PreprocessIng and Analysis
dc.date.updated 2019-02-03T04:18:56Z
dc.language.rfc3066 en
dc.rights.holder The Author(s).
dc.type.uri http://purl.org/eprint/entityType/ScholarlyWork
dc.type.uri http://purl.org/eprint/entityType/Expression
dc.type.uri http://purl.org/eprint/type/JournalArticle

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