LUCAS Versus Manual Chest Compression During Ambulance Transport : A Hemodynamic Study in a Porcine Model of Cardiac Arrest

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Magliocca , A , Olivari , D , De Giorgio , D , Zani , D , Manfredi , M , Boccardo , A , Cucino , A , Sala , G , Babini , G , Ruggeri , L , Novelli , D , Skrifvars , M B , Hardig , B M , Pravettoni , D , Staszewsky , L , Latini , R , Belloli , A & Ristagno , G 2019 , ' LUCAS Versus Manual Chest Compression During Ambulance Transport : A Hemodynamic Study in a Porcine Model of Cardiac Arrest ' , Journal of the American Heart Association , vol. 8 , no. 1 , 011189 . https://doi.org/10.1161/JAHA.118.011189

Title: LUCAS Versus Manual Chest Compression During Ambulance Transport : A Hemodynamic Study in a Porcine Model of Cardiac Arrest
Author: Magliocca, Aurora; Olivari, Davide; De Giorgio, Dana; Zani, Davide; Manfredi, Martina; Boccardo, Antonio; Cucino, Alberto; Sala, Giulia; Babini, Giovanni; Ruggeri, Laura; Novelli, Deborah; Skrifvars, Markus B.; Hardig, Bjarne Madsen; Pravettoni, Davide; Staszewsky, Lidia; Latini, Roberto; Belloli, Angelo; Ristagno, Giuseppe
Contributor: University of Helsinki, Department of Diagnostics and Therapeutics
Date: 2019-01-08
Language: eng
Number of pages: 11
Belongs to series: Journal of the American Heart Association
ISSN: 2047-9980
URI: http://hdl.handle.net/10138/298745
Abstract: Background-Mechanical chest compression (CC) is currently suggested to deliver sustained high-quality CC in a moving ambulance. This study compared the hemodynamic support provided by a mechanical piston device or manual CC during ambulance transport in a porcine model of cardiopulmonary resuscitation. Methods and Results-In a simulated urban ambulance transport, 16 pigs in cardiac arrest were randomized to 18 minutes of mechanical CC with the LUCAS (n=8) or manual CC (n=8). ECG, arterial and right atrial pressure, together with end-tidal CO2 and transthoracic impedance curve were continuously recorded. Arterial lactate was assessed during cardiopulmonary resuscitation and after resuscitation. During the initial 3 minutes of cardiopulmonary resuscitation, the ambulance was stationary, while then proceeded along a predefined itinerary. When the ambulance was stationary, CC-generated hemodynamics were equivalent in the 2 groups. However, during ambulance transport, arterial and coronary perfusion pressure, and end-tidal CO(2 )were significantly higher with mechanical CC compared with manual CC (coronary perfusion pressure: 43 +/- 4 versus 18 +/- 4 mmHg; end-tidal CO2: 31 +/- 2 versus 19 +/- 2 mmHg, P Conclusions-This model adds evidence in favor of the use of mechanical devices to provide ongoing high-quality CC and tissue perfusion during ambulance transport.
Subject: ambulance transport
cardiac arrest
cardiopulmonary resuscitation
chest compression resuscitation
manual cardiopulmonary resuscitation
mechanical cardiopulmonary resuscitation
RESUSCITATION COUNCIL GUIDELINES
2015 INTERNATIONAL CONSENSUS
CARDIOVASCULAR CARE SCIENCE
CORONARY PERFUSION-PRESSURE
TIDAL CARBON-DIOXIDE
BASIC LIFE-SUPPORT
CARDIOPULMONARY-RESUSCITATION
24-HOUR SURVIVAL
QUALITY
CPR
3121 General medicine, internal medicine and other clinical medicine
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