'Nutrimune (R)' and immune defence against pathogens in the gastrointestinal and upper respiratory tracts : evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006

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dc.contributor University of Helsinki, Department of Food and Nutrition en
dc.contributor.author EFSA Panel Dietetic Products Nutri
dc.contributor.author Heinonen, Marina
dc.date.accessioned 2019-02-06T14:34:01Z
dc.date.available 2019-02-06T14:34:01Z
dc.date.issued 2017-01
dc.identifier.citation EFSA Panel Dietetic Products Nutri & Heinonen , M 2017 , ' 'Nutrimune (R)' and immune defence against pathogens in the gastrointestinal and upper respiratory tracts : evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 ' , EFSA Journal , vol. 15 , no. 1 , 4679 . https://doi.org/10.2903/j.efsa.2017.4679 en
dc.identifier.issn 1831-4732
dc.identifier.other PURE: 121749345
dc.identifier.other PURE UUID: 817c5c54-e55f-44e1-afa1-1fbb7224d19a
dc.identifier.other WOS: 000406421600024
dc.identifier.other ORCID: /0000-0002-9930-4009/work/53825685
dc.identifier.uri http://hdl.handle.net/10138/298755
dc.description.abstract Following an application from H.J. Heinz Supply Chain Europe B.V., submitted for authorisation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 via the Competent Authority of the Netherlands, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver an opinion on the scientific substantiation of a health claim related to 'Nutrimune (R)' and immune defence against pathogens in the gastrointestinal (GI) tract and upper respiratory tract (URT). The food 'Nutrimune (R)' (a pasteurised cow's skim milk fermented with Lactobacillus paracasei CBA L74) which is the subject of the health claim is sufficiently characterised. The Panel considers that immune defence against pathogens in GI tract and URT is a beneficial physiological effect. One human intervention study from which conclusions can be drawn showed an effect of 'Nutrimune (R)' on immune defence against pathogens in the GI tract and the URT, and the results from one animal study could support an effect of 'Nutrimune (R)' on defence against pathogens in the GI tract. However, there were inconsistencies in the reporting of the process and criteria used for the diagnosis of URTI in the human intervention study, the results of this study have not been replicated, and no evidence was provided for a plausible mechanism by which 'Nutrimune (R)' could exert the claimed effect in vivo in humans. The Panel concludes that the evidence provided is insufficient to establish a cause and effect relationship between the consumption of 'Nutrimune (R)' and immune defence against pathogens in the gastrointestinal and upper respiratory tracts. (C) 2017 European Food Safety Authority. EFSA Journal published by John Wiley and Sons Ltd on behalf of European Food Safety Authority. en
dc.format.extent 14
dc.language.iso eng
dc.relation.ispartof EFSA Journal
dc.rights en
dc.subject Nutrimune (R) en
dc.subject immune defence en
dc.subject gastrointestinal tract en
dc.subject upper respiratory tract en
dc.subject infection en
dc.subject children en
dc.subject health claims en
dc.subject 416 Food Science en
dc.title 'Nutrimune (R)' and immune defence against pathogens in the gastrointestinal and upper respiratory tracts : evaluation of a health claim pursuant to Article 14 of Regulation (EC) No 1924/2006 en
dc.type Article
dc.description.version Peer reviewed
dc.identifier.doi https://doi.org/10.2903/j.efsa.2017.4679
dc.type.uri info:eu-repo/semantics/other
dc.type.uri info:eu-repo/semantics/publishedVersion
dc.contributor.pbl
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