Risk factors for death and severe neurological sequelae in childhood bacterial meningitis in sub-Saharan Africa

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Pysyväisosoite

http://hdl.handle.net/10138/299295

Lähdeviite

Pelkonen , T , Roine , I , Monteiro , L , Correia , M , Pitkäranta , A , Bernardino , L & Peltola , H 2009 , ' Risk factors for death and severe neurological sequelae in childhood bacterial meningitis in sub-Saharan Africa ' , Clinical Infectious Diseases , vol. 48 , no. 8 , pp. 1107-1110 . https://doi.org/10.1086/597463

Julkaisun nimi: Risk factors for death and severe neurological sequelae in childhood bacterial meningitis in sub-Saharan Africa
Tekijä: Pelkonen, Tuula; Roine, Irmeli; Monteiro, Lurdes; Correia, Margarida; Pitkäranta, Anne; Bernardino, Luis; Peltola, Heikki
Tekijän organisaatio: Korva-, nenä- ja kurkkutautien klinikka
Children's Hospital
Clinicum
Päiväys: 2009
Kieli: eng
Sivumäärä: 4
Kuuluu julkaisusarjaan: Clinical Infectious Diseases
ISSN: 1058-4838
DOI-tunniste: https://doi.org/10.1086/597463
URI: http://hdl.handle.net/10138/299295
Tiivistelmä: We report a morality rate of 33% among 403 children with bacterial meningitis in Angola. A fatal outcome was associated with impaired consciousness, severe dyspnea, and seizures, and severe neurological sequelae (found in 25% of our patients) was associated with delayed presentation to the hospital, impaired consciousness, and seizures. Being underweight was of secondary importance. Treatment with ceftriaxone, rather than with penicillin plus chloramphenicol, did not improve outcome.We report a morality rate of 33% among 403 children with bacterial meningitis in Angola. A fatal outcome was associated with impaired consciousness, severe dyspnea, and seizures, and severe neurological sequelae (found in 25% of our patients) was associated with delayed presentation to the hospital, impaired consciousness, and seizures. Being underweight was of secondary importance. Treatment with ceftriaxone, rather than with penicillin plus chloramphenicol, did not improve outcome.We report a morality rate of 33% among 403 children with bacterial meningitis in Angola. A fatal outcome was associated with impaired consciousness, severe dyspnea, and seizures, and severe neurological sequelae (found in 25% of our patients) was associated with delayed presentation to the hospital, impaired consciousness, and seizures. Being underweight was of secondary importance. Treatment with ceftriaxone, rather than with penicillin plus chloramphenicol, did not improve outcome.
Avainsanat: 3121 General medicine, internal medicine and other clinical medicine
Vertaisarvioitu: Kyllä
Pääsyrajoitteet: openAccess
Rinnakkaistallennettu versio: publishedVersion


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