Risk factors for death and severe neurological sequelae in childhood bacterial meningitis in sub-Saharan Africa

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http://hdl.handle.net/10138/299295

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Pelkonen , T , Roine , I , Monteiro , L , Correia , M , Pitkäranta , A , Bernardino , L & Peltola , H 2009 , ' Risk factors for death and severe neurological sequelae in childhood bacterial meningitis in sub-Saharan Africa ' , Clinical Infectious Diseases , vol. 48 , no. 8 , pp. 1107-1110 . https://doi.org/10.1086/597463

Titel: Risk factors for death and severe neurological sequelae in childhood bacterial meningitis in sub-Saharan Africa
Författare: Pelkonen, Tuula; Roine, Irmeli; Monteiro, Lurdes; Correia, Margarida; Pitkäranta, Anne; Bernardino, Luis; Peltola, Heikki
Upphovmannens organisation: Korva-, nenä- ja kurkkutautien klinikka
Children's Hospital
Clinicum
Datum: 2009
Språk: eng
Sidantal: 4
Tillhör serie: Clinical Infectious Diseases
ISSN: 1058-4838
DOI: https://doi.org/10.1086/597463
Permanenta länken (URI): http://hdl.handle.net/10138/299295
Abstrakt: We report a morality rate of 33% among 403 children with bacterial meningitis in Angola. A fatal outcome was associated with impaired consciousness, severe dyspnea, and seizures, and severe neurological sequelae (found in 25% of our patients) was associated with delayed presentation to the hospital, impaired consciousness, and seizures. Being underweight was of secondary importance. Treatment with ceftriaxone, rather than with penicillin plus chloramphenicol, did not improve outcome.We report a morality rate of 33% among 403 children with bacterial meningitis in Angola. A fatal outcome was associated with impaired consciousness, severe dyspnea, and seizures, and severe neurological sequelae (found in 25% of our patients) was associated with delayed presentation to the hospital, impaired consciousness, and seizures. Being underweight was of secondary importance. Treatment with ceftriaxone, rather than with penicillin plus chloramphenicol, did not improve outcome.We report a morality rate of 33% among 403 children with bacterial meningitis in Angola. A fatal outcome was associated with impaired consciousness, severe dyspnea, and seizures, and severe neurological sequelae (found in 25% of our patients) was associated with delayed presentation to the hospital, impaired consciousness, and seizures. Being underweight was of secondary importance. Treatment with ceftriaxone, rather than with penicillin plus chloramphenicol, did not improve outcome.
Subject: 3121 General medicine, internal medicine and other clinical medicine
Referentgranskad: Ja
Användningsbegränsning: openAccess
Parallelpublicerad version: publishedVersion


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