Risk factors for suicide in depression in Finland : first-hospitalized patients followed up to 24 years

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dc.contributor.author Aaltonen, Kari I.
dc.contributor.author Isometsä, Erkki
dc.contributor.author Sund, Reijo
dc.contributor.author Pirkola, Sami
dc.date.accessioned 2019-02-27T22:25:15Z
dc.date.available 2021-12-17T22:02:51Z
dc.date.issued 2019-02
dc.identifier.citation Aaltonen , K I , Isometsä , E , Sund , R & Pirkola , S 2019 , ' Risk factors for suicide in depression in Finland : first-hospitalized patients followed up to 24 years ' , Acta Psychiatrica Scandinavica , vol. 139 , no. 2 , pp. 154-163 . https://doi.org/10.1111/acps.12990
dc.identifier.other PURE: 119698514
dc.identifier.other PURE UUID: af5330c9-b995-4a83-ac4d-4c6732643f48
dc.identifier.other RIS: urn:25EA4341D947CDF6616311E77C0A013E
dc.identifier.other Scopus: 85058418429
dc.identifier.other WOS: 000456702900005
dc.identifier.other ORCID: /0000-0002-6268-8117/work/53827343
dc.identifier.uri http://hdl.handle.net/10138/299681
dc.description.abstract Objective To examine longitudinally risk factors for suicide in depression, and gender differences in risk factors and suicide methods. Method We linked data from (i) The Finnish Hospital Discharge Register, (ii) the Census Register of Statistics Finland, and (iii) Statistics Finland's register on causes of deaths. All 56 826 first-hospitalized patients (25 188 men, 31 638 women) in Finland in 1991-2011 with a principal diagnosis of depressive disorder were followed up until death (2587 suicides) or end of the year 2014 (maximum 24 years). Results Clinical characteristics (severe depression adjusted hazard ratio [AHR] 1.19 [95% CI 1.08-1.30]; psychotic depression AHR 1.45 [1.30-1.62]; and comorbid alcohol dependence AHR 1.26 [1.13-1.41]), male gender (AHR 2.07 [1.91-2.24]), higher socioeconomic status and living alone at first hospitalization were long-term predictors of suicide deaths. Highest risk was associated with previous suicide attempts (cumulative probability 15.4% [13.7-17.3%] in men, 8.5% [7.3-9.7%] in women). Gender differences in risk factors were modest, but in lethal methods prominent. Conclusion Sociodemographic and clinical characteristics at first hospitalization predict suicide in the long term. Inpatients with previous suicide attempts constitute a high-risk group. Despite some gender differences in risk factors, those in lethal methods may better explain gender disparity in risk. en
dc.format.extent 10
dc.language.iso eng
dc.relation.ispartof Acta Psychiatrica Scandinavica
dc.rights cc_by_nc
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject depression
dc.subject suicide
dc.subject cohort studies
dc.subject risk factors
dc.subject gender differences
dc.subject GENDER DIFFERENCES
dc.subject DISORDERS
dc.subject REGISTER
dc.subject NATIONWIDE
dc.subject DISCHARGE
dc.subject INDIVIDUALS
dc.subject PREDICTORS
dc.subject MORTALITY
dc.subject SEVERITY
dc.subject BEHAVIOR
dc.subject 3124 Neurology and psychiatry
dc.title Risk factors for suicide in depression in Finland : first-hospitalized patients followed up to 24 years en
dc.type Article
dc.contributor.organization Doctoral Programme in Clinical Research
dc.contributor.organization Department of Psychiatry
dc.contributor.organization Clinicum
dc.contributor.organization University of Helsinki
dc.contributor.organization Department of Social Research (2010-2017)
dc.contributor.organization HUS Psychiatry
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1111/acps.12990
dc.relation.issn 0001-690X
dc.rights.accesslevel openAccess
dc.type.version acceptedVersion
dc.type.version publishedVersion

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