Breast Lesion Excision System in the diagnosis and treatment of intraductal papillomas - A feasibility study

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dc.contributor.author Niinikoski, Laura
dc.contributor.author Hukkinen, Katja
dc.contributor.author Leidenius, Marjut H. K.
dc.contributor.author Ståhls, Anders
dc.contributor.author Meretoja, Tuomo J.
dc.date.accessioned 2019-03-15T22:53:22Z
dc.date.available 2021-12-17T22:02:23Z
dc.date.issued 2018-01
dc.identifier.citation Niinikoski , L , Hukkinen , K , Leidenius , M H K , Ståhls , A & Meretoja , T J 2018 , ' Breast Lesion Excision System in the diagnosis and treatment of intraductal papillomas - A feasibility study ' , European Journal of Surgical Oncology , vol. 44 , no. 1 , pp. 59-66 . https://doi.org/10.1016/j.ejso.2017.10.213
dc.identifier.other PURE: 100388516
dc.identifier.other PURE UUID: 7af5e321-cf87-410a-90a5-c211dfff04bc
dc.identifier.other WOS: 000423247000009
dc.identifier.other Scopus: 85034664538
dc.identifier.other ORCID: /0000-0002-2691-0710/work/42819891
dc.identifier.uri http://hdl.handle.net/10138/300143
dc.description.abstract Objectives: This study aims to evaluate the feasibility of Breast Lesion Excision System (BLES) in the treatment of intraductal papillomas. Material and methods: All patients with a needle biopsy-based suspicion of an intraductal papilloma who consequently underwent a BLES procedure at Helsinki University Hospital between 2011 and 2016 were included in this retrospective study. The purpose of the BLES procedure was either to excise the entire lesion or in few cases to achieve better sampling. Results: In total, 74 patients underwent 80 BLES procedures. Pathological diagnosis after the BLES biopsy confirmed an intraductal papilloma without atypia in 43 lesions, whereas 10 lesions were upgraded to high-risk lesions (HRL) with either atypical ductal hyperplasia or lobular carcinoma in situ. Five cases were upgraded to malignancy, two were invasive ductal carcinomas and three were ductal carcinoma in situ. Additionally, 18 lesions were diagnosed as other benign lesions. Four procedures failed. Complete excision with BLES was achieved in 19 out of 43 intraductal papillomas, 6 out of 10 HRL and two out of five malignant lesions. No major complications occurred. The BLES procedure was adequate in the management of the 71 breast lesions. Conclusion: The BLES procedure is an acceptable method for the management of small benign and high-risk breast lesions such as intraductal papillomas in selected patients. Thus, a great amount of diagnostic surgical biopsies can be avoided. (C) 2017 Elsevier Ltd, BASO similar to The Association for Cancer Surgery, and the European Society of Surgical Oncology. All rights reserved. en
dc.format.extent 8
dc.language.iso eng
dc.relation.ispartof European Journal of Surgical Oncology
dc.rights.uri info:eu-repo/semantics/openAccess
dc.subject Intraductal papilloma
dc.subject Breast Lesion Excision System (BLES)
dc.subject High risk lesion
dc.subject Surgical excision
dc.subject Core needle biopsy
dc.subject CORE-NEEDLE-BIOPSY
dc.subject PAPILLARY LESIONS
dc.subject SURGICAL EXCISION
dc.subject FOLLOW-UP
dc.subject HIGH-RISK
dc.subject RADIOFREQUENCY
dc.subject MANAGEMENT
dc.subject CARCINOMA
dc.subject ACCURACY
dc.subject FEATURES
dc.subject 3122 Cancers
dc.subject 3126 Surgery, anesthesiology, intensive care, radiology
dc.title Breast Lesion Excision System in the diagnosis and treatment of intraductal papillomas - A feasibility study en
dc.type Article
dc.contributor.organization HUS Comprehensive Cancer Center
dc.contributor.organization Department of Oncology
dc.contributor.organization Department of Diagnostics and Therapeutics
dc.contributor.organization Clinicum
dc.contributor.organization University of Helsinki
dc.contributor.organization HUS Medical Imaging Center
dc.contributor.organization II kirurgian klinikka
dc.contributor.organization Department of Surgery
dc.contributor.organization HUSLAB
dc.contributor.organization Medicum
dc.contributor.organization Department of Pathology
dc.description.reviewstatus Peer reviewed
dc.relation.doi https://doi.org/10.1016/j.ejso.2017.10.213
dc.relation.issn 0748-7983
dc.rights.accesslevel openAccess
dc.type.version publishedVersion

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