Features of borderline personality disorder as a mediator of the relation between childhood traumatic experiences and psychosis-like experiences in patients with mood disorder

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Baryshnikov , I , Aaltonen , K , Suvisaari , J , Koivisto , M , Heikkinen , M , Joffe , G & Isometsä , E 2018 , ' Features of borderline personality disorder as a mediator of the relation between childhood traumatic experiences and psychosis-like experiences in patients with mood disorder ' , European Psychiatry , vol. 49 , pp. 9-15 . https://doi.org/10.1016/j.eurpsy.2017.12.005

Title: Features of borderline personality disorder as a mediator of the relation between childhood traumatic experiences and psychosis-like experiences in patients with mood disorder
Author: Baryshnikov, Ilya; Aaltonen, Kari; Suvisaari, Jaana; Koivisto, Maaria; Heikkinen, Martti; Joffe, Grigori; Isometsä, Erkki
Other contributor: University of Helsinki, Department of Psychiatry
University of Helsinki, Department of Psychiatry
University of Helsinki, Clinicum
University of Helsinki, Department of Psychiatry
University of Helsinki, Clinicum
University of Helsinki, Department of Psychiatry
University of Helsinki, Department of Psychiatry



Date: 2018-03
Language: eng
Number of pages: 7
Belongs to series: European Psychiatry
ISSN: 0924-9338
DOI: https://doi.org/10.1016/j.eurpsy.2017.12.005
URI: http://hdl.handle.net/10138/300576
Abstract: Background: Psychosis-like experiences (PEs) are common in patients with non-psychotic disorders. Several factors predict reporting of PEs in mood disorders, including mood-associated cognitive biases, anxiety and features of borderline personality disorder (BPD). Childhood traumatic experiences (CEs), often reported by patients with BPD, are an important risk factor for mental disorders. We hypothesized that features of BPD may mediate the relationship between CEs and PEs. In this study, we investigated the relationships between self-reported PEs, CEs and features of BPD in patients with mood disorders. Methods: As part of the Helsinki University Psychiatric Consortium study, McLean Screening Instrument (MSI), Community Assessment of Psychic Experiences (CAPE-42) and Trauma and Distress Scale (TADS) were filled in by patients with mood disorders (n = 282) in psychiatric care. Correlation coefficients between total scores of scales and their dimensions were estimated, multiple regression and mediation analyses were conducted. Results: Total scores of MSI correlated strongly with scores of the CAPE-42 dimension "frequency of positive symptoms" (rho = 0.56; p Conclusions: Self-reported cognitive-perceptual symptoms of BPD fully mediate, while affective, behavioural and interpersonal symptoms only partially mediate the relationships between CEs and PEs. Recognition of co-morbid features of BPD in patients with mood disorders reporting PEs is essential. (c) 2017 Elsevier Masson SAS. All rights reserved.
Subject: Borderline personality disorder
Psychotic-like symptoms
Childhood traumatic experiences
Mediation analysis
MAJOR DEPRESSIVE DISORDER
MCLEAN SCREENING INSTRUMENT
CLINICAL HIGH-RISK
SEXUAL-ABUSE
DISSOCIATIVE SYMPTOMS
GENERAL-POPULATION
BIPOLAR DISORDER
MSI-BPD
HALLUCINATIONS
MALTREATMENT
3124 Neurology and psychiatry
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