Comparison of reconstruction and acquisition choices for quantitative T2* maps and synthetic contrasts

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Ruuth , R , Kuusela , L , Mäkelä , T , Melkas , S & Korvenoja , A 2019 , ' Comparison of reconstruction and acquisition choices for quantitative T2* maps and synthetic contrasts ' , European journal of radiology open , vol. 6 , pp. 42-48 .

Title: Comparison of reconstruction and acquisition choices for quantitative T2* maps and synthetic contrasts
Author: Ruuth, Riikka; Kuusela, Linda; Mäkelä, Teemu; Melkas, Susanna; Korvenoja, Antti
Contributor organization: Department of Physics
Department of Diagnostics and Therapeutics
University of Helsinki
Neurologian yksikkö
Department of Neurosciences
HUS Medical Imaging Center
HUS Neurocenter
Date: 2019
Language: eng
Number of pages: 7
Belongs to series: European journal of radiology open
ISSN: 2352-0477
Abstract: Aim and scope: A Gradient Echo Plural Contrast Imaging technique (GEPCI) is a post-processing method, which can be used to obtain quantitative T2* values and generate multiple synthetic contrasts from a single acquisition. However, scan duration and image reconstruction from k-space data present challenges in a clinical workflow. This study aimed at optimizing image reconstruction and acquisition duration to facilitate a post-processing method for synthetic image contrast creation in clinical settings. Materials and methods: This study consists of tests using the American College of Radiology (ACR) image quality phantom, two healthy volunteers, four mild traumatic brain injury patients and four small vessel disease patients. The measurements were carried out on a 3.0 T scanner with multiple echo times. Reconstruction from k-space data and DICOM data with two different coil-channel combination modes were investigated. Partial Fourier techniques were tested to optimize the scanning time. Conclusions: Sum of squares coil-channel combination produced artifacts in phase images, but images created with adaptive combination were artifact-free. The voxel-wise median signed difference of T2* between the vendor's adaptive channel combination and k-space reconstruction modes was 2.9 +/- 0.7 ms for white matter and 4.5 +/- 0.6 ms for gray matter. Relative white matter/gray matter contrast of all synthetic images and contrast-to-noise ratio of synthetic T1-weighted images were almost equal between reconstruction modes. Our results indicate that synthetic contrasts can be generated from the vendor's DICOM data with the adaptive combination mode without affecting the quantitative T2* values or white matter/gray matter contrast.
Subject: 3112 Neurosciences
3124 Neurology and psychiatry
3126 Surgery, anesthesiology, intensive care, radiology
114 Physical sciences
Magnetic resonance imaging
Image quality
Quantitative MRI
MRI reconstruction
T2* mapping
Synthetic contrasts
Peer reviewed: Yes
Rights: cc_by
Usage restriction: openAccess
Self-archived version: publishedVersion

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