Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma : AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines

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Gregoire , V , Evans , M , Quynh-Thu Le , Bourhis , J , Budach , V , Chen , A , Eisbruch , A , Feng , M , Giralt , J , Gupta , T , Hamoir , M , Helito , J K , Hu , C , Hunter , K , Johansen , J , Kaanders , J , Laskar , S G , Lee , A , Maingon , P , Mäkitie , A , Micciche , F , Nicolai , P , O'Sullivan , B , Poitevin , A , Porceddu , S , Skiadowski , K , Tribius , S , Waldron , J , Wee , J , Yao , M , Yom , S S , Zimmermann , F & Grau , C 2018 , ' Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma : AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines ' , Radiotherapy and Oncology , vol. 126 , no. 1 , pp. 3-24 . https://doi.org/10.1016/j.radonc.2017.10.016

Title: Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma : AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines
Author: Gregoire, Vincent; Evans, Mererid; Quynh-Thu Le,; Bourhis, Jean; Budach, Volker; Chen, Amy; Eisbruch, Abraham; Feng, Mei; Giralt, Jordi; Gupta, Tejpal; Hamoir, Marc; Helito, Juliana K.; Hu, Chaosu; Hunter, Keith; Johansen, Jorgen; Kaanders, Johannes; Laskar, Sarbani Ghosh; Lee, Anne; Maingon, Philippe; Mäkitie, Antti; Micciche, Francesco; Nicolai, Piero; O'Sullivan, Brian; Poitevin, Adela; Porceddu, Sandro; Skiadowski, Krzysztof; Tribius, Silke; Waldron, John; Wee, Joseph; Yao, Min; Yom, Sue S.; Zimmermann, Frank; Grau, Cai
Contributor: University of Helsinki, Clinicum
Date: 2018-01
Language: eng
Number of pages: 22
Belongs to series: Radiotherapy and Oncology
ISSN: 0167-8140
URI: http://hdl.handle.net/10138/301086
Abstract: Purpose: Few studies have reported large inter-observer variations in target volume selection and delineation in patients treated with radiotherapy for head and neck squamous cell carcinoma. Consensus guidelines have been published for the neck nodes (see Gregoire et al., 2003, 2014), but such recommendations are lacking for primary tumour delineation. For the latter, two main schools of thoughts are prevailing, one based on geometric expansion of the Gross Tumour Volume (GTV) as promoted by DAHANCA, and the other one based on anatomical expansion of the GTV using compartmentalization of head and neck anatomy. Method: For each anatomic location within the larynx, hypopharynx, oropharynx and oral cavity, and for each T-stage, the DAHANCA proposal has been comprehensively reviewed and edited to include anatomic knowledge into the geometric Clinical Target Volume (CTV) delineation concept. A first proposal was put forward by the leading authors of this publication (VG and CG) and discussed with opinion leaders in head and neck radiation oncology from Europe, Asia, Australia/New Zealand, North America and South America to reach a worldwide consensus. Results: This consensus proposes two CTVs for the primary tumour, the so called CTV-P1 and CVT-P2, corresponding to a high and lower tumour burden, and which should be associated with a high and a lower dose prescription, respectively. Conclusion: Implementation of these guidelines in the daily practice of radiation oncology should contribute to reduce treatment variations from clinicians to clinicians, facilitate the conduct of multi institutional clinical trials, and contribute to improved care of patients with head and neck carcinoma. (C) 2017 Elsevier B.V. All rights reserved.
Subject: Clinical Target Volume (CTV)
Gross Tumour Volume (GTV)
Radiotherapy
Head and neck
Guideline
EUROPEAN LARYNGOLOGICAL SOCIETY
TRANSORAL-LASER-MICROSURGERY
NECK-CANCER
RADIATION-THERAPY
TONSIL CANCER
ADVANCED HEAD
NODE LEVELS
FDG-PET
RADIOTHERAPY
CLASSIFICATION
3122 Cancers
3126 Surgery, anesthesiology, intensive care, radiology
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