Prevalence, Temporal Evolution and Impact on Survival of Ventricular Conduction Blocks in Patients with Acute Coronary Syndrome and Cardiogenic Shock

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CardShock Study Investigators , Great Network , Tolppanen , H , Javanainen , T , Nieminen , T , Harjola , V-P , Jurkko , R & Lassus , J 2018 , ' Prevalence, Temporal Evolution and Impact on Survival of Ventricular Conduction Blocks in Patients with Acute Coronary Syndrome and Cardiogenic Shock ' , American Journal of Cardiology , vol. 122 , no. 2 , pp. 199-205 . https://doi.org/10.1016/j.amjcard.2018.04.008

Title: Prevalence, Temporal Evolution and Impact on Survival of Ventricular Conduction Blocks in Patients with Acute Coronary Syndrome and Cardiogenic Shock
Author: Tolppanen, Heli; Javanainen, Tuija; Sans-Rosello, Jordi; Parenica, Jiri; Nieminen, Tuomo; Pavlusova, Marie; Masip, Josep; Köber, Lars; Banaszewski, Marek; Sionis, Alessandro; Spinar, Jindrich; Harjola, Veli-Pekka; Jurkko, Raija; Lassus, Johan
Contributor: University of Helsinki, HUS Heart and Lung Center
University of Helsinki, Department of Medicine
University of Helsinki, Department of Medicine
University of Helsinki, HUS Emergency Medicine and Services
University of Helsinki, Kardiologian yksikkö
University of Helsinki, HUS Heart and Lung Center
Date: 2018-07-15
Number of pages: 7
Belongs to series: American Journal of Cardiology
ISSN: 0002-9149
URI: http://hdl.handle.net/10138/301094
Abstract: Changes in QRS duration and pattern are regarded to reflect severe ischemia in acute coronary syndromes (ACS), and ventricular conduction blocks (VCBs) are recognized high-risk markers in both ACS and acute heart failure. Our aim was to evaluate the prevalence, temporal evolution, association with clinical and angiographic parameters, and impact on mortality of VCBs in ACS-related cardiogenic shock (CS). Data of 199 patients with ACS-related CS from a prospective multinational cohort were evaluated with electrocardiogram data from baseline and day 3. VCBs including left or right bundle branch block, right bundle branch block and hemiblock, isolated hemiblocks, and unspecified intraventricular conduction delay were assessed. Fifty percent of patients had a VCB at baseline; these patients were older, had poorer left ventricular function and had more often left main disease compared with those without VCB. One-year mortality was over 2-fold in patients with VCB compared with those without VCB (68% vs 32%, p
Subject: ACUTE MYOCARDIAL-INFARCTION
BUNDLE-BRANCH BLOCK
PRESENTING ELECTROCARDIOGRAM
CLINICAL CHARACTERISTICS
PROGNOSTIC-SIGNIFICANCE
PRIMARY ANGIOPLASTY
RISK PREDICTION
HEART-FAILURE
QRS COMPLEX
ST-SEGMENT
3121 Internal medicine
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