First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring

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Helle , E I T , Biegley , P , Knowles , J W , Leader , J B , Pendergrass , S , Yang , W , Reaven , G R , Shaw , G M , Ritchie , M & Priest , J R 2018 , ' First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring ' , The Journal of Pediatrics , vol. 195 , pp. 275-278 . https://doi.org/10.1016/j.jpeds.2017.10.046

Title: First Trimester Plasma Glucose Values in Women without Diabetes are Associated with Risk for Congenital Heart Disease in Offspring
Author: Helle, Emmi I. T.; Biegley, Preston; Knowles, Joshua W.; Leader, Joseph B.; Pendergrass, Sarah; Yang, Wei; Reaven, Gerald R.; Shaw, Gary M.; Ritchie, Marylyn; Priest, James R.
Contributor: University of Helsinki, Kivelä Lab
Date: 2018-04
Language: eng
Number of pages: 4
Belongs to series: The Journal of Pediatrics
ISSN: 0022-3476
URI: http://hdl.handle.net/10138/301211
Abstract: In a retrospective study of 19 171 mother-child dyads, elevated random plasma glucose values during early pregnancy were directly correlated with increased risk for congenital heart disease in offspring. Plasma glucose levels proximal to the period of cardiac development may represent a modifiable risk factor for congenital heart disease in expectant mothers without diabetes.
Subject: INSULIN SENSITIVITY
MELLITUS
3123 Gynaecology and paediatrics
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