One-year weight losses in the Tianjin Gestational Diabetes Mellitus Prevention Programme : A randomized clinical trial

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Liu , H , Wang , L , Zhang , S , Leng , J , Li , N , Li , W , Wang , J , Tian , H , Qi , L , Yang , X , Yu , Z , Tuomilehto , J & Hu , G 2018 , ' One-year weight losses in the Tianjin Gestational Diabetes Mellitus Prevention Programme : A randomized clinical trial ' , Diabetes, obesity and metabolism , vol. 20 , no. 5 , pp. 1246-1255 . https://doi.org/10.1111/dom.13225

Title: One-year weight losses in the Tianjin Gestational Diabetes Mellitus Prevention Programme : A randomized clinical trial
Author: Liu, Huikun; Wang, Leishen; Zhang, Shuang; Leng, Junhong; Li, Nan; Li, Weiqin; Wang, Jing; Tian, Huiguang; Qi, Lu; Yang, Xilin; Yu, Zhijie; Tuomilehto, Jaakko; Hu, Gang
Contributor: University of Helsinki, Clinicum
Date: 2018-05
Language: eng
Number of pages: 10
Belongs to series: Diabetes, obesity and metabolism
ISSN: 1462-8902
URI: http://hdl.handle.net/10138/301260
Abstract: Aims: To report the weight loss findings after the first year of a lifestyle intervention trial among women with gestational diabetes mellitus (GDM). Methods: A total of 1180 women with GDM were randomly assigned (1: 1) to receive a 4-year lifestyle intervention (intervention group, n = 586) or standard care (control group, n = 594) between August 2009 and July 2011. Major elements of the intervention included 6 face-to-face sessions with study dieticians and two telephone calls in the first year, and two individual sessions and two telephone calls in each subsequent year. Results: Among 79% of participants who completed the year 1 trial, mean weight loss was 0.82 kg (1.12% of initial weight) in the intervention group and 0.09 kg (0.03% of initial weight) in the control group (P=.001). In a prespecified subgroup analysis of people who completed the trial, weight loss was more pronounced in women who were overweight (body mass index = 24 kg/m(2)) at baseline: mean weight loss 2.01 kg (2.87% of initial weight) in the intervention group and 0.44 kg (0.52% of initial weight) in the control group (P Conclusion: The 1-year lifestyle intervention led to significant weight losses after delivery in women who had GDM, and the effect was more pronounced in women who were overweight at baseline.
Subject: gestational diabetes
randomized clinical trials
weight loss
LIFE-STYLE INTERVENTION
IMPAIRED GLUCOSE-TOLERANCE
BODY-MASS INDEX
CHINESE WOMEN
POSTPARTUM
TYPE-2
RISK
METAANALYSIS
ASSOCIATION
PREGNANCY
3142 Public health care science, environmental and occupational health
3121 General medicine, internal medicine and other clinical medicine
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