Oral lichen sclerosus : a systematic review of reported cases and two new cases

Show full item record




Kakko , T , Salo , T & Siponen , M K 2018 , ' Oral lichen sclerosus : a systematic review of reported cases and two new cases ' , International Journal of Dermatology , vol. 57 , no. 5 , pp. 521-528 . https://doi.org/10.1111/ijd.13870

Title: Oral lichen sclerosus : a systematic review of reported cases and two new cases
Author: Kakko, Tuomas; Salo, Tuula; Siponen, Maria K.
Contributor organization: Clinicum
Department of Oral and Maxillofacial Diseases
Date: 2018-05
Language: eng
Number of pages: 8
Belongs to series: International Journal of Dermatology
ISSN: 0011-9059
DOI: https://doi.org/10.1111/ijd.13870
URI: http://hdl.handle.net/10138/301262
Abstract: Lichen sclerosus (LS) is a chronic inflammatory mucocutaneous disease with uncertain etiology. It occurs as white plaque-like lesions mostly in the anogenital skin. Oral mucosal involvement is extremely rare. This study aims to summarize the features of published oral lichen sclerosus (OLS) and two new cases. A systematic search of the English literature from 1955 to 2016 was performed in MEDLINE, Scopus, and Web of Science, and cross-references were searched manually. Search phrases included lichen sclerosus, mouth, oral, lip, palate, floor of mouth, tongue, gingiva, buccal mucosa, and mouth diseases. Cases with clinical and histopathological confirmation of diagnosis of OLS were included. A total of 41 (39 published and 2 new) histologically confirmed OLS cases were available. The median age of OLS patients was 31 years, and 66% of the patients were female. Most of the OLS lesions were asymptomatic. They were located in the labial mucosa (n = 20), lip (n = 15), buccal mucosa (n = 14), gingiva (n = 12), tongue (n = 12), and palate (n = 7). OLS is rare and typically presents as asymptomatic, white, plaque-like lesions. Malignant transformation of preexisting OLS has not been reported.
3121 General medicine, internal medicine and other clinical medicine
Peer reviewed: Yes
Rights: unspecified
Usage restriction: openAccess
Self-archived version: publishedVersion

Files in this item

Total number of downloads: Loading...

Files Size Format View
Oral_lichen_sclerosus.pdf 331.0Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record