Anterior cruciate ligament transection alters the n-3/n-6 fatty acid balance in the lapine infrapatellar fat pad

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Mustonen , A-M , Käkelä , R , Finnilä , M A J , Sawatsky , A , Korhonen , R K , Saarakkala , S , Herzog , W , Paakkonen , T & Nieminen , P 2019 , ' Anterior cruciate ligament transection alters the n-3/n-6 fatty acid balance in the lapine infrapatellar fat pad ' , Lipids in Health and Disease , vol. 18 , no. 67 , 67 . https://doi.org/10.1186/s12944-019-1008-5

Title: Anterior cruciate ligament transection alters the n-3/n-6 fatty acid balance in the lapine infrapatellar fat pad
Author: Mustonen, Anne-Mari; Käkelä, Reijo; Finnilä, Mikko A. J.; Sawatsky, Andrew; Korhonen, Rami K.; Saarakkala, Simo; Herzog, Walter; Paakkonen, Tommi; Nieminen, Petteri
Contributor: University of Helsinki, Physiology and Neuroscience
Date: 2019-03-18
Language: eng
Number of pages: 9
Belongs to series: Lipids in Health and Disease
ISSN: 1476-511X
URI: http://hdl.handle.net/10138/301531
Abstract: The infrapatellar fat pad (IFP) of the knee joint has received lots of attention recently due to its emerging role in the pathogenesis of osteoarthritis (OA), where it displays an inflammatory phenotype. The aim of the present study was to examine the infrapatellar fatty acid (FA) composition in a rabbit (Oryctolagus cuniculus) model of early OA created by anterior cruciate ligament transection (ACLT).
Subject: ARTICULAR-CARTILAGE
Anterior cruciate ligament transection
BONE
KNEE OSTEOARTHRITIS
Knee joint
MODEL
MRI
N-3 polyunsaturated fatty acids
N-6 polyunsaturated fatty acids
Oryctolagus cuniculus
Osteoarthritis
1182 Biochemistry, cell and molecular biology
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