Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas

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http://hdl.handle.net/10138/302405

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UF HLTH Study Grp 2018 , ' Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas ' , Environment International , vol. 116 , pp. 186-196 . https://doi.org/10.1016/j.envint.2018.04.021

Title: Two-way effect modifications of air pollution and air temperature on total natural and cardiovascular mortality in eight European urban areas
Author: UF HLTH Study Grp
Date: 2018-07
Language: eng
Number of pages: 11
Belongs to series: Environment International
ISSN: 0160-4120
URI: http://hdl.handle.net/10138/302405
Abstract: Background: Although epidemiological studies have reported associations between mortality and both ambient air pollution and air temperature, it remains uncertain whether the mortality effects of air pollution are modified by temperature and vice versa. Moreover, little is known on the interactions between ultrafine particles (diameter Objective: We investigated whether the short-term associations of particle number concentration (PNC in the ultrafine range ( Methods: We first analyzed air temperature-stratified associations between air pollution and total natural (nonaccidental) and cardiovascular mortality as well as air pollution-stratified temperature-mortality associations using city-specific over-dispersed Poisson additive models with a distributed lag nonlinear temperature term in each city. All models were adjusted for long-term and seasonal trend, day of the week, influenza epidemics, and population dynamics due to summer vacation and holidays. City-specific effect estimates were then pooled using random-effects meta-analysis. Results: Pooled associations between air pollutants and total and cardiovascular mortality were overall positive and generally stronger at high relatively compared to low air temperatures. For example, on days with high air temperatures (> 75th percentile), an increase of 10,000 particles/cm(3) in PNC corresponded to a 2.51% (95% CI: 0.39%, 4.67%) increase in cardiovascular mortality, which was significantly higher than that on days with low air temperatures (<25th percentile) [-0.18% (95% CI: -0.97%, 0.62%)]. On days with high air pollution (> 50th percentile), both heat-and cold-related mortality risks increased. Conclusion: Our findings showed that high temperature could modify the effects of air pollution on daily mortality and high air pollution might enhance the air temperature effects.
Subject: Ultrafine particles
Particulate matter
Ozone
Air temperature
Mortality
Effect modification
PARTICLE NUMBER CONCENTRATION
TIME-SERIES-ANALYSIS
MYOCARDIAL-INFARCTION SURVIVORS
9 FRENCH CITIES
PARTICULATE MATTER
ULTRAFINE PARTICLES
UNITED-STATES
TEMPORAL VARIATION
EPIDEMIOLOGIC EVIDENCE
AMBIENT-TEMPERATURE
3121 General medicine, internal medicine and other clinical medicine
3142 Public health care science, environmental and occupational health
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