Outcomes of High-Frequency Gastric Electric Stimulation for the Treatment of Severe, Medically Refractory Gastroparesis in Finland

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Laine , M , Siren , J , Koskenpato , J , Punkkinen , J , Rantanen , T , Typpö , I , Kokkola , A & Sallinen , V 2018 , ' Outcomes of High-Frequency Gastric Electric Stimulation for the Treatment of Severe, Medically Refractory Gastroparesis in Finland ' , Scandinavian Journal of Surgery , vol. 107 , no. 2 , pp. 124-129 . https://doi.org/10.1177/1457496917748222

Title: Outcomes of High-Frequency Gastric Electric Stimulation for the Treatment of Severe, Medically Refractory Gastroparesis in Finland
Author: Laine, M.; Siren, J.; Koskenpato, J.; Punkkinen, J.; Rantanen, T.; Typpö, I.; Kokkola, A.; Sallinen, V.
Contributor: University of Helsinki, Clinicum
University of Helsinki, II kirurgian klinikka
University of Helsinki, Department of Medicine
University of Helsinki, Clinicum
University of Helsinki, II kirurgian klinikka
University of Helsinki, Pertti Panula / Principal Investigator
Date: 2018-06
Language: eng
Number of pages: 6
Belongs to series: Scandinavian Journal of Surgery
ISSN: 1457-4969
URI: http://hdl.handle.net/10138/302406
Abstract: Background and Aims: Severe, medically uncontrollable gastroparesis is a rare entity, which can be treated using a high-frequency gastric electric stimulator implanted surgically. Previous follow-ups have proven positive outcomes with gastric electric stimulator in patients with gastroparesis. The aim of this study was to evaluate the efficacy and safety of gastric electric stimulator in patients, in whom gastroparesis could not be controlled by conservative means in our country. Materials and Methods: This is a retrospective multi-center cohort comprising all patients who had been implanted gastric electric stimulator for severe, medically refractory gastroparesis during 2007-2015 in Finland. Results: Fourteen patients underwent implantation of gastric electrical stimulator without any postoperative complications. Laparoscopic approach was used in 13 patients (93%). Prior implantation, all patients needed frequent hospitalization for parenteral feeding, 13 had severe nausea, 11 had severe vomiting, 10 had notable weight loss, and 6 had frequent abdominal pain. After operation, none of the patients required parenteral feeding, 11 patients (79%) gained median of 5.1 kg in weight (P <0.01), and symptoms were relieved markedly in 8 and partially in 3 patients (79%). Of partial responders, two continued to experience occasional vomiting and one mild nausea. Five patients needed medication for gastroparesis after the operation. One patient did not get any relief of symptoms, but gained 6 kg in weight. No major late complications occurred. Conclusion: Gastric electrical stimulator seems to improve the nutritional status and give clear relief of the symptoms of severe, medically uncontrollable gastroparesis. Given the low number of operations, gastric electrical stimulator seems to be underused in Finland.
Subject: High-frequency gastric electric stimulation
gastroparesis
laparoscopy
multi-center cohort
complications
Finland
SEVERE CHRONIC CONSTIPATION
BOTULINUM TOXIN
FUNCTIONAL DYSPEPSIA
CONTROLLED-TRIAL
PRUCALOPRIDE
SYMPTOMS
INJECTION
3126 Surgery, anesthesiology, intensive care, radiology
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