Self-reported psychosis-like experiences in patients with mood disorders

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Baryshnikov , I , Suvisaari , J , Aaltonen , K , Koivisto , M , Melartin , T , Näätänen , P , Suominen , K , Karpov , B , Heikkinen , M , Oksanen , J , Paunio , T , Joffe , G & Isometsä , E 2018 , ' Self-reported psychosis-like experiences in patients with mood disorders ' , European Psychiatry , vol. 51 , pp. 90-97 .

Title: Self-reported psychosis-like experiences in patients with mood disorders
Author: Baryshnikov, I.; Suvisaari, J.; Aaltonen, K.; Koivisto, M.; Melartin, T.; Näätänen, P.; Suominen, K.; Karpov, B.; Heikkinen, M.; Oksanen, J.; Paunio, T.; Joffe, G.; Isometsä, E.
Contributor organization: Department of Psychiatry
University of Helsinki
Department of Computer Science
HUS Psychiatry
Date: 2018-06
Language: eng
Number of pages: 8
Belongs to series: European Psychiatry
ISSN: 0924-9338
Abstract: Background: Self-reported psychosis-like experiences (PEs) may be common in patients with mood disorders, but their clinical correlates are not well known. We investigated their prevalence and relationships with self-reported symptoms of depression, mania, anxiety, borderline (BPD) and schizotypal (SPD) personality disorders among psychiatric patients with mood disorders. Methods: The Community Assessment of Psychic Experiences (CAPE-42), Mood Disorder Questionnaire (MDQ), McLean Screening Instrument (MSI), The Beck Depressive Inventory (BDI), Overall Anxiety Severity and Impairment Scale (OASIS) and Schizotypal Personality Questionnaire-Brief form (SPQ-B) were filled in by patients with mood disorders (n = 282) from specialized care. Correlation coefficients between total scores and individual items of CAPE-42 and BDI, SPQ-B, MSI and MDQ were estimated. Hierarchical multivariate regression analysis was conducted to examine factors influencing the frequency of self-reported PE. Results: PEs are common in patients with mood disorders. The "frequency of positive symptoms" score of CAPE-42 correlated strongly with total score of SPQ-B (rho = 0.63; P <0.001) and moderately with total scores of BDI, MDQ OASIS and MSI (rho varied from 0.37 to 0.56; P <0.001). Individual items of CAPE-42 correlated moderately with specific items of BDI, MDQ SPQ-B and MSI (r(phi) varied from 0.2 to 0.5; P <0.001). Symptoms of anxiety, mania or hypomania and BPD were significant predictors of the "frequency of positive symptoms" score of CAPE-42. Conclusions: Several, state- and trait-related factors may underlie self-reported PEs among mood disorder patients. These include cognitive-perceptual distortions of SPD; distrustfulness, identity disturbance, dissociative and affective symptoms of BPD; and cognitive biases related to depressive or manic symptoms. (C) 2016 Elsevier Masson SAS. All rights reserved.
Subject: Psychosis-like symptoms
Mood disorder patients
Borderline personality disorder
3124 Neurology and psychiatry
Peer reviewed: Yes
Usage restriction: openAccess
Self-archived version: publishedVersion

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