Early Lifestyle Interventions in People with Impaired Glucose Tolerance in Northern Colombia : The DEMOJUAN Project

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http://hdl.handle.net/10138/303568

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Barengo , N C , Acosta , T , Arrieta , A , Ricaurte , C , Smits , D , Florez , K & Tuomilehto , J O 2019 , ' Early Lifestyle Interventions in People with Impaired Glucose Tolerance in Northern Colombia : The DEMOJUAN Project ' , International Journal of Environmental Research and Public Health , vol. 16 , no. 8 , 1403 . https://doi.org/10.3390/ijerph16081403

Title: Early Lifestyle Interventions in People with Impaired Glucose Tolerance in Northern Colombia : The DEMOJUAN Project
Author: Barengo, Noel C.; Acosta, Tania; Arrieta, Astrid; Ricaurte, Carlos; Smits, Dins; Florez, Karen; Tuomilehto, Jaakko O.
Contributor: University of Helsinki, Faculty of Medicine
University of Helsinki, Clinicum
Date: 2019-04-02
Language: eng
Number of pages: 13
Belongs to series: International Journal of Environmental Research and Public Health
ISSN: 1660-4601
URI: http://hdl.handle.net/10138/303568
Abstract: Background: The objective of the demonstration project for type 2 diabetes prevention in the Barranquilla and Juan Mina (DEMOJUAN) study was to investigate the extent to which it is possible to reach normal glucose metabolism with early lifestyle interventions in people at high risk of type 2 diabetes (prediabetes), compared with those who receive standard usual care. Methods: DEMOJUAN was a randomized controlled trial conducted in Juan Mina and Barranquilla, Northern Colombia. Eligible participants were randomized into one of three groups (control group, initial nutritional intervention, and initial physical activity intervention). The duration of the intervention was 24 months. The main study outcome in the present analysis was reversion to normoglycemia. Relative risks and their corresponding 95% confidence intervals were calculated for reversal to normoglycemia and T2D incidence. Results: There was no statistically significant association between the intervention groups and reversion to normoglycemia. The relative risk of reversion to normoglycemia was 0.88 (95% CI 0.70-1.12) for the initial nutritional intervention group participants and 0.95 (95% CI 0.75-1.20) for the initial physical activity intervention group participants. Conclusions: Our study did not find any statistically significant differences in reversion to normoglycemia or the development of type 2 diabetes between the intervention groups and the control group in this population.
Subject: glucose metabolism disorders
primary prevention
South America
population
field trial
DIABETES PREVENTION PROGRAM
PHYSICAL-ACTIVITY QUESTIONNAIRE
LEISURE-TIME
RISK SCORE
REAL-LIFE
TYPE-2
DIET
VALIDATION
REDUCTION
COMMUNITY
3142 Public health care science, environmental and occupational health
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