Relation of Use of Red Blood Cell Transfusion After Acute Coronary Syndrome to Long-Term Mortality

Show full item record



Permalink

http://hdl.handle.net/10138/303658

Citation

Allonen , J , Nieminen , M S , Hiippala , S & Sinisalo , J 2018 , ' Relation of Use of Red Blood Cell Transfusion After Acute Coronary Syndrome to Long-Term Mortality ' , American Journal of Cardiology , vol. 121 , no. 12 , pp. 1496-1504 . https://doi.org/10.1016/j.amjcard.2018.02.035

Title: Relation of Use of Red Blood Cell Transfusion After Acute Coronary Syndrome to Long-Term Mortality
Author: Allonen, Jaakko; Nieminen, Markku S.; Hiippala, Seppo; Sinisalo, Juha
Contributor organization: Clinicum
Department of Medicine
Kardiologian yksikkö
University of Helsinki
Doctoral Programme in Drug Research
Department of Diagnostics and Therapeutics
Anestesiologian yksikkö
HUS Heart and Lung Center
HUS Perioperative, Intensive Care and Pain Medicine
Date: 2018-06-15
Language: eng
Number of pages: 9
Belongs to series: American Journal of Cardiology
ISSN: 0002-9149
DOI: https://doi.org/10.1016/j.amjcard.2018.02.035
URI: http://hdl.handle.net/10138/303658
Abstract: Registry studies have associated red blood cell (RBC) transfusion with increased in hospital mortality in patients with acute coronary syndrome (ACS). The impact on long-term mortality after 1-year follow-up remains unknown. Consecutive patients with ACS (n = 2,009) of a prospective Genetic Predisposition of Coronary Artery Disease cohort were followed for a median of 8.6 years (95% confidence interval [CI] 8.59 to 8.69). After discharge, 1,937 (96%) patients survived for over 30 days. Of those survivors, a subgroup of previously transfusion-nave patients 85/1,937 (4.4%) who had received at least 1 RBC transfusion during hospitalization were compared with 1,278/1,937 patients (66.0%) who had not received any transfusion either during the hospitalization or the entire follow-up. Unadjusted long-term mortality was significantly higher in the patients transfused with RBC compared with their counterparts not transfused with RBC (58.8% vs 20.3%, p
Subject: ACUTE MYOCARDIAL-INFARCTION
INTERVENTION
ANEMIA
IMPACT
OUTCOMES
DISEASE
TRIAL
ANGIOPLASTY
THRESHOLDS
REGISTERS
3121 General medicine, internal medicine and other clinical medicine
Peer reviewed: Yes
Usage restriction: openAccess
Self-archived version: publishedVersion


Files in this item

Total number of downloads: Loading...

Files Size Format View
1_s2.0_S0002914918302716_main.pdf 672.4Kb PDF View/Open

This item appears in the following Collection(s)

Show full item record