Relation of Use of Red Blood Cell Transfusion After Acute Coronary Syndrome to Long-Term Mortality

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Allonen , J , Nieminen , M S , Hiippala , S & Sinisalo , J 2018 , ' Relation of Use of Red Blood Cell Transfusion After Acute Coronary Syndrome to Long-Term Mortality ' , American Journal of Cardiology , vol. 121 , no. 12 , pp. 1496-1504 . https://doi.org/10.1016/j.amjcard.2018.02.035

Title: Relation of Use of Red Blood Cell Transfusion After Acute Coronary Syndrome to Long-Term Mortality
Author: Allonen, Jaakko; Nieminen, Markku S.; Hiippala, Seppo; Sinisalo, Juha
Contributor: University of Helsinki, Clinicum
University of Helsinki, Doctoral Programme in Drug Research
University of Helsinki, Department of Diagnostics and Therapeutics
University of Helsinki, Clinicum
Date: 2018-06-15
Language: eng
Number of pages: 9
Belongs to series: American Journal of Cardiology
ISSN: 0002-9149
URI: http://hdl.handle.net/10138/303658
Abstract: Registry studies have associated red blood cell (RBC) transfusion with increased in hospital mortality in patients with acute coronary syndrome (ACS). The impact on long-term mortality after 1-year follow-up remains unknown. Consecutive patients with ACS (n = 2,009) of a prospective Genetic Predisposition of Coronary Artery Disease cohort were followed for a median of 8.6 years (95% confidence interval [CI] 8.59 to 8.69). After discharge, 1,937 (96%) patients survived for over 30 days. Of those survivors, a subgroup of previously transfusion-nave patients 85/1,937 (4.4%) who had received at least 1 RBC transfusion during hospitalization were compared with 1,278/1,937 patients (66.0%) who had not received any transfusion either during the hospitalization or the entire follow-up. Unadjusted long-term mortality was significantly higher in the patients transfused with RBC compared with their counterparts not transfused with RBC (58.8% vs 20.3%, p
Subject: ACUTE MYOCARDIAL-INFARCTION
INTERVENTION
ANEMIA
IMPACT
OUTCOMES
DISEASE
TRIAL
ANGIOPLASTY
THRESHOLDS
REGISTERS
3121 General medicine, internal medicine and other clinical medicine
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