Mucin 16 and kallikrein 13 as potential prognostic factors in colon cancer: Results of an oncological 92-multiplex immunoassay

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Björkman , K , Mustonen , H , Kaprio , T , Haglund , C & Böckelman , C 2019 , ' Mucin 16 and kallikrein 13 as potential prognostic factors in colon cancer: Results of an oncological 92-multiplex immunoassay ' , Tumor Biology , vol. 41 , no. 7 , 1010428319860728 . https://doi.org/10.1177/1010428319860728

Title: Mucin 16 and kallikrein 13 as potential prognostic factors in colon cancer: Results of an oncological 92-multiplex immunoassay
Author: Björkman, Kajsa; Mustonen, Harri; Kaprio, Tuomas; Haglund, Caj; Böckelman, Camilla
Contributor: University of Helsinki, Research Programs Unit
University of Helsinki, Translational Cancer Biology (TCB) Research Programme
University of Helsinki, Translational Cancer Biology (TCB) Research Programme
University of Helsinki, HUS Abdominal Center
University of Helsinki, Clinicum
Date: 2019-07-02
Language: eng
Number of pages: 10
Belongs to series: Tumor Biology
ISSN: 1010-4283
URI: http://hdl.handle.net/10138/303938
Abstract: Colon cancer represents one of the most common cancers in the world. Despite improved treatment, mortality remains high. In order to improve the assessment of prognosis for colon cancer patients, identifying new prognostic markers remains necessary. We analyzed preoperative serum samples from 148 colon cancer patients surgically treated at Helsinki University Hospital from 1998 through 2002 using a multiplex proximity extension assay (Oncology II panel, Olink Bioscience, Uppsala, Sweden), a panel constituting 92 immunological and oncological markers. We performed univariate and multivariate analyses on these patients and calculated the disease-specific survival among patients using the log-rank test for Kaplan?Meier estimates. In the univariate survival analysis of 92 biomarkers, 26 resulted in p?
Subject: 3122 Cancers
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