Anomalous aortic origin of coronary arteries : Early results on clinical management from an international multicenter study

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Padalino , M A , Franchetti , N , Sarris , G E , Hazekamp , M , Carrel , T , Frigiola , A , Horer , J , Roussin , R , Cleuziou , J , Meyns , B , Fragata , J , Telles , H , Polimenakos , A C , Francois , K , Veshti , A , Salminen , J , Gonzalez Rocafort , A , Nosal , M , Vedovelli , L , Protopapas , E , Tumbarello , R , Merola , A , Pegoraro , C , Motta , R , Boccuzzo , G , Sojak , V , Lo Rito , M , Caldaroni , F , Corrado , D , Basso , C & Stellin , G 2019 , ' Anomalous aortic origin of coronary arteries : Early results on clinical management from an international multicenter study ' , International Journal of Cardiology , vol. 291 , pp. 189-193 . https://doi.org/10.1016/j.ijcard.2019.02.007

Title: Anomalous aortic origin of coronary arteries : Early results on clinical management from an international multicenter study
Author: Padalino, Massimo A.; Franchetti, Nicola; Sarris, George E.; Hazekamp, Mark; Carrel, Thierry; Frigiola, Alessandro; Horer, Jurgen; Roussin, Regine; Cleuziou, Julie; Meyns, Bart; Fragata, Jose; Telles, Helena; Polimenakos, Anastasios C.; Francois, Katrien; Veshti, Altin; Salminen, Jukka; Gonzalez Rocafort, Alvaro; Nosal, Matej; Vedovelli, Luca; Protopapas, Eleftherios; Tumbarello, Roberto; Merola, Assunta; Pegoraro, Cinzia; Motta, Raffaella; Boccuzzo, Giovanna; Sojak, Vladimir; Lo Rito, Mauro; Caldaroni, Federica; Corrado, Domenico; Basso, Cristina; Stellin, Giovanni
Contributor: University of Helsinki, HUS Children and Adolescents
Date: 2019-09-15
Language: eng
Number of pages: 5
Belongs to series: International Journal of Cardiology
ISSN: 0167-5273
URI: http://hdl.handle.net/10138/304284
Abstract: Background: Anomalous aortic origin of coronary arteries (AAOCA) is a rare abnormality, whose optimal management is still undefined. We describe early outcomes in patients treated with different management strategies. Methods: This is a retrospective clinicalmulticenter study including patients with AAOCA, undergoing or not surgical treatment. Patients with isolated high coronary take off and associated major congenital heart disease were excluded. Preoperative, intraoperative, anatomical and postoperative data were retrieved from a common database. Results: Among 217 patients, 156 underwent Surgical repair (median age 39 years, IQR: 15-53), while 61 were Medical (median age 15 years, IQR: 8-52), inwhomAAOCA was incidentally diagnosed during screening or clinical evaluations. Surgical patients were more often symptomatic when compared to medical ones (87.2% vs 44.3%, p b 0.001). Coronary unroofing was the most frequent procedure (56.4%). Operative mortality was 1.3% (2 patients with preoperative severe heart failure). At a median follow up of 18 months (range 0.1-23 years), 89.9% of survivors are in NYHA Conclusions: Surgery for AAOCA is safe andwith low morbidity. When compared to Medical patients, who remain on exercise restriction and medical therapy, surgical patients have a benefit in terms of symptoms and return to normal life. Since the long term-risk of sudden cardiac death is still unknown, we currently recommend accurate long term surveillance in all patients with AAOCA. (C) 2019 The Authors. Published by Elsevier B.V.
Subject: Clinical management
Surgery
Anomalous coronary arteries
Congenital
Outcomes
QUALITY-OF-LIFE
SUDDEN-DEATH
EXERCISE PERFORMANCE
SURGICAL REPAIR
OPPOSITE SINUS
POPULATION
STATEMENT
CHILDREN
3126 Surgery, anesthesiology, intensive care, radiology
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