Comorbidity and retirement in cervical dystonia

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http://hdl.handle.net/10138/305076

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Ortiz , R M , Scheperjans , F , Mertsalmi , T & Pekkonen , E 2019 , ' Comorbidity and retirement in cervical dystonia ' , Journal of Neurology , vol. 266 , no. 9 , pp. 2216-2223 . https://doi.org/10.1007/s00415-019-09402-0

Title: Comorbidity and retirement in cervical dystonia
Author: Ortiz, Rebekka M.; Scheperjans, Filip; Mertsalmi, Tuomas; Pekkonen, Eero
Contributor: University of Helsinki, HUS Neurocenter
University of Helsinki, HUS Neurocenter
University of Helsinki, HUS Neurocenter
University of Helsinki, HUS Neurocenter
Date: 2019-09
Language: eng
Number of pages: 8
Belongs to series: Journal of Neurology
ISSN: 0340-5354
URI: http://hdl.handle.net/10138/305076
Abstract: Background Cervical dystonia (CD) is the most common form of dystonia. The onset of CD is usually before 60 years of age and it may cause severe functional and psychosocial impairment in everyday life. Recently non-motor symptoms have been reported to occur in CD substantially affecting the quality of life. Methods/patients We studied comorbidities of patients with primary focal CD in Finland based on ICD-10 codes obtained from the care registry and patient records of 937 confirmed adult isolated focal CD patients between the years 2007-2016. The retirement months and diagnosis of retirement were calculated from pension registry information. The results were compared with 3746 age and gender-matched controls. Results Most prominent comorbidities with primary focal CD were depression (14%), anxiety (7%), and back pain (11%). The retirement age was significantly younger in CD patients compared to control group controls (59.0 years, 95% CI 58.5-59.5 vs. 61.7 years, 95% CI 61.6-61.9) years, p <0.001). For dystonia patients the most common diagnoses for retirement due to sickness were dystonia (51%), depression (14%), and anxiety (8%). Patients with anxiety and depression retired earlier than other dystonia patients. Discussion Cervical dystonia considerably reduces working ability and leads to earlier retirement. Anxiety and depression are most notable comorbidities and their co-occurrence further reduces working ability. Our results suggest that more health care resources should be administered in treatment of CD to longer maintain working ability of CD patients. Further, psychiatric comorbidities should be taken into consideration in CD treatment.
Subject: Dystonia
Cervical dystonia
Comorbidity
Working ability
Pension
QUALITY-OF-LIFE
PSYCHIATRIC COMORBIDITY
SPASMODIC TORTICOLLIS
ESSENTIAL TREMOR
BOTULINUM TOXIN
PAIN
IMPACT
DETERMINANTS
DEPRESSION
MYELOPATHY
3124 Neurology and psychiatry
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