Diabetes alone does not impair recovery from uneventful cataract surgery

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Danni , R , Taipale , C , Ilveskoski , L & Tuuminen , R 2018 , ' Diabetes alone does not impair recovery from uneventful cataract surgery ' , American Journal of Ophthalmology , vol. 198 , pp. 37–44 . https://doi.org/10.1016/j.ajo.2018.09.030

Title: Diabetes alone does not impair recovery from uneventful cataract surgery
Author: Danni, Reeta; Taipale, Claudia; Ilveskoski, Lotta; Tuuminen, Raimo
Contributor: University of Helsinki, University of Helsinki
Date: 2018-10-09
Number of pages: 8
Belongs to series: American Journal of Ophthalmology
ISSN: 0002-9394
URI: http://hdl.handle.net/10138/305918
Abstract: Purpose To study the outcomes of uneventful cataract surgery in diabetic patients without retinal complications. Setting Conducted at Kymenlaakso Central Hospital, Kotka, Finland. Design A post-hoc treatment analysis using data from 2 double-blind RCTs. Methods A total of 276 eyes of 266 patients undergoing routine cataract surgery were included in the study. Patients with type I or II diabetes (N=56 eyes) were compared to non-diabetic patients (N=220 eyes). Clinical evaluation was conducted by the operating physician, and outcome measures taken before surgery and day 28 were recorded by a research technician. Results Patient age, gender distribution and all baseline ophthalmic and surgical parameters were comparable for the non-diabetic and diabetic patient groups. Increase in aqueous flare 6.3±16.4pu/msec vs. 3.7±8.9pu/msec (mean±SD; P=0.282), CRT 12.0±38.2μm vs. 5.9±15.8μm (P=0.256), corrected distance visual acuity 0.57±0.31decimals vs. 0.53±0.35decimals (P=0.259), and patient satisfaction 9.3±0.9 vs. 9.2±1.1 (P=0.644) were comparable for non-diabetic and diabetic patients. In eyes with steroid monotherapy (N=64), CRT increased 38.1±72.8μm in non-diabetic patients compared to 7.8±6.6μm in diabetic ones (P=0.010). In eyes with nonsteroidal anti-inflammatory drug (NSAID) monotherapy (N=157), CRT increased 5.7±18.4μm in non-diabetic patients compared to 6.2±20.5μm in diabetic ones (P=0.897). Among eyes with steroid and NSAID combination therapy (N=55), CRT increased 3.6±4.1μm in non-diabetic patients compared to 2.9±3.2μm in diabetic ones (P=0.606). At 28 days, pseudophakic cystoid macular edema (PCME) was reported in eight eyes, of which seven in non-diabetic patients (P=1.000). Conclusions Diabetic patients showed less changes in CRT when compared to controls in steroid monotherapy. Other outcome measurement shows no statistical differences.
Subject: 3125 Otorhinolaryngology, ophthalmology
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