Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation

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http://hdl.handle.net/10138/305997

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Laine , A-L , Barres , B , Numminen , E & Siren , J P 2019 , ' Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation ' , eLife , vol. 8 , 47091 . https://doi.org/10.7554/eLife.47091

Title: Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation
Author: Laine, Anna-Liisa; Barres, Benoit; Numminen, Elina; Siren, Jukka P.
Other contributor: University of Helsinki, Organismal and Evolutionary Biology Research Programme
University of Helsinki, Organismal and Evolutionary Biology Research Programme
University of Helsinki, Research Centre for Ecological Change
University of Helsinki, Organismal and Evolutionary Biology Research Programme



Date: 2019-06-18
Language: eng
Number of pages: 17
Belongs to series: eLife
ISSN: 2050-084X
DOI: https://doi.org/10.7554/eLife.47091
URI: http://hdl.handle.net/10138/305997
Abstract: Many pathogens possess the capacity for sex through outcrossing, despite being able to reproduce also asexually and/or via selfing. Given that sex is assumed to come at a cost, these mixed reproductive strategies typical of pathogens have remained puzzling. While the ecological and evolutionary benefits of outcrossing are theoretically well-supported, support for such benefits in pathogen populations are still scarce. Here, we analyze the epidemiology and genetic structure of natural populations of an obligate fungal pathogen, Podosphaera plantaginis. We find that the opportunities for outcrossing vary spatially. Populations supporting high levels of coinfection -a prerequisite of sex - result in hotspots of novel genetic diversity. Pathogen populations supporting coinfection also have a higher probability of surviving winter. Jointly our results show that outcrossing has direct epidemiological consequences as well as a major impact on pathogen population genetic diversity, thereby providing evidence of ecological and evolutionary benefits of outcrossing in pathogens.
Subject: 1181 Ecology, evolutionary biology
APPROXIMATE BAYESIAN COMPUTATION
RED-QUEEN
SEX
EVOLUTIONARY
POPULATION
RECOMBINATION
MAINTENANCE
RESISTANCE
COINFECTION
DIVERSITY
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