Tolska , H K , Hamunen , K , Takala , A & Kontinen , V K 2019 , ' Systematic review of analgesics and dexamethasone for post-tonsillectomy pain in adults ' , British Journal of Anaesthesia , vol. 123 , no. 2 , pp. E397-E411 . https://doi.org/10.1016/j.bja.2019.04.063
Title: | Systematic review of analgesics and dexamethasone for post-tonsillectomy pain in adults |
Author: | Tolska, H. K.; Hamunen, K.; Takala, A.; Kontinen, V. K. |
Contributor organization: | Anestesiologian yksikkö HUS Perioperative, Intensive Care and Pain Medicine University of Helsinki Vesa Kontinen / Principal Investigator University Management Department of Pharmacology |
Date: | 2019-08 |
Language: | eng |
Number of pages: | 15 |
Belongs to series: | British Journal of Anaesthesia |
ISSN: | 0007-0912 |
DOI: | https://doi.org/10.1016/j.bja.2019.04.063 |
URI: | http://hdl.handle.net/10138/306021 |
Abstract: | Background: Intense pain can last several days after tonsillectomy. It is often undertreated and improved analgesic strategies that can be safely used at home are needed. Methods: We conducted a systematic review and meta-analysis on the effectiveness of systemic medications used for post-tonsillectomy pain in adult and adolescent (13 yr old) patients. Studies were identified from PubMed, the Cochrane Library, and by hand searching reference lists from studies and review articles. Randomised, double-blind, placebo-controlled studies reporting on pain intensity or use of rescue analgesia were included. Results: Twenty-nine randomised controlled trials representing 1816 subjects met the inclusion criteria. Follow-up time was Conclusions: Single analgesics and dexamethasone provide only a weak to moderate effect for post-tonsillectomy pain on the day of operation and thus a multimodal analgesic strategy is recommended. Short follow-up times and clinical heterogeneity of studies limit the usefulness of results. |
Subject: |
adolescent
adult analgesics dexamethasone multimodal analgesia postoperative pain tonsillectomy NONSTEROIDAL ANTIINFLAMMATORY DRUGS POSTOPERATIVE PAIN DOUBLE-BLIND REDUCES PAIN PARACETAMOL DEXTROMETHORPHAN KETOPROFEN EFFICACY RISK GABAPENTIN/PREGABALIN 3126 Surgery, anesthesiology, intensive care, radiology |
Peer reviewed: | Yes |
Usage restriction: | openAccess |
Self-archived version: | publishedVersion |
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